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ChemicalBook >> CAS DataBase List >> Nalmefene hydrochloride

Nalmefene hydrochloride

Nalmefene hydrochloride price.
  • $118 - $404.35
  • Product name: Nalmefene hydrochloride
  • CAS: 58895-64-0
  • MF: C21H26ClNO3
  • MW: 375.89
  • EINECS:232-572-4
  • MDL Number:MFCD27937056
  • Synonyms:Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, hydrochloride, (5alpha)-;Unii-K7K69qc05x;(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diolhydrochloride;(5a)-17-(CyclopropylMethyl)-6-Methylene-4,5-epoxyMorphinan-3,14-diol;Morphinan-3,14-diol,17-(cyclopropylMethyl)-4,5-epoxy-6-Methylene-, hydrochloride (1:1), (5a)-;(4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol,hydrochloride;17-(cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol hydrochloride;nalmefene hydrochloride
5 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Crysdot
  • Tocris
Package
  • 50
  • 1MG
  • 5MG
  • 10MG
  • 250mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009358
  • Product descriptionNALMEFENE HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$404.35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009358
  • Product descriptionNALMEFENE HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$402.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009358
  • Product descriptionNALMEFENE HYDROCHLORIDE 95.00%
  • Packaging1MG
  • Price$400.43
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001381
  • Product descriptionNalmefeneHydrochloride 98%
  • Packaging250mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4085
  • Product descriptionNalmefenehydrochloride ≥99%(HPLC)
  • Packaging50
  • Price$118
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0009358 NALMEFENE HYDROCHLORIDE 95.00% 10MG $404.35 2021-12-16 Buy
American Custom Chemicals Corporation API0009358 NALMEFENE HYDROCHLORIDE 95.00% 5MG $402.75 2021-12-16 Buy
American Custom Chemicals Corporation API0009358 NALMEFENE HYDROCHLORIDE 95.00% 1MG $400.43 2021-12-16 Buy
Crysdot CD31001381 NalmefeneHydrochloride 98% 250mg $160 2021-12-16 Buy
Tocris 4085 Nalmefenehydrochloride ≥99%(HPLC) 50 $118 2021-12-16 Buy

Properties

Melting point :180-185°
storage temp. :Desiccate at RT
solubility :Soluble in Water (up to 25 mg/ml).
form :solid
pka :7.63(at 25℃)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
CAS DataBase Reference :58895-64-0

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P285 In case of inadequate ventilation wear respiratory protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

Nalmefene hydrochloride has been introduced in the U.S.A. for opioid reversal following surgery, and in the reversal of opioid overdoses and epidurally administered narcotics. Nalmefene is an opioid antagonist that inhibits respiratory, analgesic and subjective effects of opioids. It has a higher potency, a longer duration of action, and superior bioavailability than the structurally related naltrexone. Nalmefene has a wide spectrum of biological activity and is in clinical trials for the treatment of interstitial cystitis, recalcitrant pruritus of cholestasis, stroke, rheumatoid arthritis, shock, CNS trauma, and alcoholism. Studies indicate that nalmefene does not induce morphine-like effects and has no apparent abuse potential.

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