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ChemicalBook >> CAS DataBase List >> Luminespib

Luminespib

Luminespib price.
  • $50 - $7048
  • Product name: Luminespib
  • CAS: 747412-49-3
  • MF: C26H31N3O5
  • MW: 465.54
  • EINECS:
  • MDL Number:MFCD14635361
  • Synonyms:5-[2,4-Dihydroxy-5-isopropylphenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]-3-isoxazolecarboxamide;AUY922 (NVP-AUY922);VER 52296;VER-52296;NVP-AUY922;AUY 922;LuMinespib;Luminespib (AUY-922, NVP-AUY922)
42 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • SynQuest Laboratories
  • TRC
  • Usbiological
Package
  • 5MG
  • 2x5mg
  • 10MG
  • 20mg
  • 25MG
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10mM(in 1mL DMSO)
  • 2g
  • ManufacturerAK Scientific
  • Product numberX7556
  • Product description5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
  • Packaging5g
  • Price$7048
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000918
  • Product descriptionNVP-AUY922 95.00%
  • Packaging5MG
  • Price$742.21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000918
  • Product descriptionNVP-AUY922 95.00%
  • Packaging10MG
  • Price$778.33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000918
  • Product descriptionNVP-AUY922 95.00%
  • Packaging25MG
  • Price$897.67
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4057
  • Product descriptionAUY922(NVP-AUY922)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4057
  • Product descriptionAUY922(NVP-AUY922)
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4057
  • Product descriptionAUY922(NVP-AUY922)
  • Packaging10mM(in 1mL DMSO)
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4057
  • Product descriptionAUY922(NVP-AUY922)
  • Packaging25mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4057
  • Product descriptionAUY922(NVP-AUY922)
  • Packaging100mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0032
  • Product descriptionNVP-AUY922 >99%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0032
  • Product descriptionNVP-AUY922 >99%
  • Packaging10mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIFK0032
  • Product descriptionNVP-AUY922 >99%
  • Packaging25mg
  • Price$196
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR16660
  • Product description5-[2,4-Dihydroxy-5-isopropylphenyl]-N-ethyl-4-{4-[(morpholin-4-yl)methyl]phenyl}isoxazole-3-carboxamide
  • Packaging25mg
  • Price$464
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR16660
  • Product description5-[2,4-Dihydroxy-5-isopropylphenyl]-N-ethyl-4-{4-[(morpholin-4-yl)methyl]phenyl}isoxazole-3-carboxamide
  • Packaging100mg
  • Price$792
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60199
  • Product descriptionLuminespib(NVP-AUY922)
  • Packaging20mg
  • Price$338
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1542
  • Product descriptionNVP-AUY922-VER52296|Luminespib 98%
  • Packaging2x5mg
  • Price$110
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7556 5-(2,4-dihydroxy-5-isopropylphenyl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide 5g $7048 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000918 NVP-AUY922 95.00% 5MG $742.21 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000918 NVP-AUY922 95.00% 10MG $778.33 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000918 NVP-AUY922 95.00% 25MG $897.67 2021-12-16 Buy
ApexBio Technology A4057 AUY922(NVP-AUY922) 5mg $50 2021-12-16 Buy
ApexBio Technology A4057 AUY922(NVP-AUY922) 10mg $70 2021-12-16 Buy
ApexBio Technology A4057 AUY922(NVP-AUY922) 10mM(in 1mL DMSO) $75 2021-12-16 Buy
ApexBio Technology A4057 AUY922(NVP-AUY922) 25mg $150 2021-12-16 Buy
ApexBio Technology A4057 AUY922(NVP-AUY922) 100mg $350 2021-12-16 Buy
Apolloscientific BIFK0032 NVP-AUY922 >99% 5mg $73 2021-12-16 Buy
Apolloscientific BIFK0032 NVP-AUY922 >99% 10mg $102 2021-12-16 Buy
Apolloscientific BIFK0032 NVP-AUY922 >99% 25mg $196 2021-12-16 Buy
Apolloscientific OR16660 5-[2,4-Dihydroxy-5-isopropylphenyl]-N-ethyl-4-{4-[(morpholin-4-yl)methyl]phenyl}isoxazole-3-carboxamide 25mg $464 2021-12-16 Buy
Apolloscientific OR16660 5-[2,4-Dihydroxy-5-isopropylphenyl]-N-ethyl-4-{4-[(morpholin-4-yl)methyl]phenyl}isoxazole-3-carboxamide 100mg $792 2021-12-16 Buy
Arctom CFN60199 Luminespib(NVP-AUY922) 20mg $338 2021-12-16 Buy
Axon Medchem Axon1542 NVP-AUY922-VER52296|Luminespib 98% 2x5mg $110 2021-12-16 Buy

Properties

Melting point :180-184°C
Boiling point :640.1±55.0 °C(Predicted)
Density :1.234
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :8.47±0.48(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
CAS DataBase Reference :747412-49-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Luminespib (AUY-922, NVP-AUY922) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Phase 2.

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