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ChemicalBook >> CAS DataBase List >> JAK3 INHIBITOR I

JAK3 INHIBITOR I

JAK3 INHIBITOR I price.
  • $18 - $6383
  • Product name: JAK3 INHIBITOR I
  • CAS: 202475-60-3
  • MF: C16H15N3O3
  • MW: 297.31
  • EINECS:
  • MDL Number:MFCD01862614
  • Synonyms:4-(4'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE;JAK3 INHIBITOR I;WHI-P131;Janex 1;A JAK3 inhibitor WHI-P131;4-(6,7-dimethoxyquinazolin-4-ylamino)phenol;WHI-P131(Janex 1);JANEX-1;WHI-P131
40 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1MG
  • 5mg
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberJ11727
  • Product descriptionJANEX-1
  • Packaging25mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ54868
  • Product descriptionJANEX-1
  • Packaging250mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA712945
  • Product descriptionJANEX-1 98+%
  • Packaging5mg
  • Price$18
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA712945
  • Product descriptionJANEX-1 98+%
  • Packaging10mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA712945
  • Product descriptionJANEX-1 98+%
  • Packaging25mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA712945
  • Product descriptionJANEX-1 98+%
  • Packaging50mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA712945
  • Product descriptionJANEX-1 98+%
  • Packaging100mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA712945
  • Product descriptionJANEX-1 98+%
  • Packaging1g
  • Price$435
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000949
  • Product descriptionJANEX-1 95.00%
  • Packaging1MG
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000949
  • Product descriptionJANEX-1 95.00%
  • Packaging5MG
  • Price$703.86
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000949
  • Product descriptionJANEX-1 95.00%
  • Packaging25MG
  • Price$1034.48
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3515
  • Product descriptionJANEX-1
  • Packaging10mM(in 1mL DMSO)
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3515
  • Product descriptionJANEX-1
  • Packaging5mg
  • Price$97
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3515
  • Product descriptionJANEX-1
  • Packaging10mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3515
  • Product descriptionJANEX-1
  • Packaging50mg
  • Price$570
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb545853
  • Product descriptionWHI-P131 >98%
  • Packaging10mg
  • Price$154.7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J11727 JANEX-1 25mg $94 2021-12-16 Buy
AK Scientific J54868 JANEX-1 250mg $195 2021-12-16 Buy
Ambeed A712945 JANEX-1 98+% 5mg $18 2021-12-16 Buy
Ambeed A712945 JANEX-1 98+% 10mg $26 2021-12-16 Buy
Ambeed A712945 JANEX-1 98+% 25mg $45 2021-12-16 Buy
Ambeed A712945 JANEX-1 98+% 50mg $66 2021-12-16 Buy
Ambeed A712945 JANEX-1 98+% 100mg $99 2021-12-16 Buy
Ambeed A712945 JANEX-1 98+% 1g $435 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000949 JANEX-1 95.00% 1MG $460 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000949 JANEX-1 95.00% 5MG $703.86 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000949 JANEX-1 95.00% 25MG $1034.48 2021-12-16 Buy
ApexBio Technology A3515 JANEX-1 10mM(in 1mL DMSO) $90 2021-12-16 Buy
ApexBio Technology A3515 JANEX-1 5mg $97 2021-12-16 Buy
ApexBio Technology A3515 JANEX-1 10mg $173 2021-12-16 Buy
ApexBio Technology A3515 JANEX-1 50mg $570 2021-12-16 Buy
Biorbyt Ltd orb545853 WHI-P131 >98% 10mg $154.7 2021-12-16 Buy

Properties

Boiling point :468.1±40.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: 18 mg/mL, soluble
form :solid
pka :10.06±0.26(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Protect from moisture. Solutions in DMSO may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 μM). Janex-1 has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases. Janex-1 acts as a potent inhibitor of glioblastoma cell adhesion and migration and is also reported to block thrombin-induced platelet aggregation.

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