Ivabradine hydrochloride
- $5 - $1802
- Product name: Ivabradine hydrochloride
- CAS: 148849-67-6
- MF: C27H37ClN2O5
- MW: 505.05
- EINECS:638-798-3
- MDL Number:MFCD00929899
- Synonyms:Ivabradine hydrochloride;3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride;Ivabradine hydrochloride, >=99%;IVABRADINE HYDROCHLORIDE-OTHER COMPOUNDSCONTAINING AN UNFUSED PYRAZOLE RING(WHETHER OR NOT HYDROGENATED)IN THE STRUCTUR;3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride;Corlentor;S-16257;(7,8-Dimethoxy 3-(3-(((1S)-(4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one hydrochloride
51 prices
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Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 10
- 5mg
- 10mg
- 50
- 50mg
- 100mg
- 200MG
- 250mg
- 5g
- 10g
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberE147
- Product descriptionIvabradineHCl
- Packaging5mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103870
- Product descriptionIvabradine hydrochloride 98+%
- Packaging10mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103870
- Product descriptionIvabradine hydrochloride 98+%
- Packaging50mg
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103870
- Product descriptionIvabradine hydrochloride 98+%
- Packaging100mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103870
- Product descriptionIvabradine hydrochloride 98+%
- Packaging250mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103870
- Product descriptionIvabradine hydrochloride 98+%
- Packaging1g
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA103870
- Product descriptionIvabradine hydrochloride 98+%
- Packaging5g
- Price$279
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000615
- Product descriptionIVABRADINE HYDROCHLORIDE 95.00%
- Packaging10MG
- Price$133.35
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1360
- Product descriptionIvabradineHCl
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1360
- Product descriptionIvabradineHCl
- Packaging10mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS426912
- Product descriptionIvabradine hydrochloride ≥98%
- Packaging10mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS426912
- Product descriptionIvabradine hydrochloride ≥98%
- Packaging50mg
- Price$9
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS426912
- Product descriptionIvabradine hydrochloride ≥98%
- Packaging100mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS426912
- Product descriptionIvabradine hydrochloride ≥98%
- Packaging250mg
- Price$29
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS426912
- Product descriptionIvabradine hydrochloride ≥98%
- Packaging1g
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS426912
- Product descriptionIvabradine hydrochloride ≥98%
- Packaging5g
- Price$276
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | E147 | IvabradineHCl | 5mg | $29 | 2021-12-16 | Buy |
Ambeed | A103870 | Ivabradine hydrochloride 98+% | 10mg | $5 | 2021-12-16 | Buy |
Ambeed | A103870 | Ivabradine hydrochloride 98+% | 50mg | $9 | 2021-12-16 | Buy |
Ambeed | A103870 | Ivabradine hydrochloride 98+% | 100mg | $16 | 2021-12-16 | Buy |
Ambeed | A103870 | Ivabradine hydrochloride 98+% | 250mg | $29 | 2021-12-16 | Buy |
Ambeed | A103870 | Ivabradine hydrochloride 98+% | 1g | $76 | 2021-12-16 | Buy |
Ambeed | A103870 | Ivabradine hydrochloride 98+% | 5g | $279 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0000615 | IVABRADINE HYDROCHLORIDE 95.00% | 10MG | $133.35 | 2021-12-16 | Buy |
ApexBio Technology | B1360 | IvabradineHCl | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
ApexBio Technology | B1360 | IvabradineHCl | 10mg | $45 | 2021-12-16 | Buy |
Arctom | AS426912 | Ivabradine hydrochloride ≥98% | 10mg | $5 | 2021-12-16 | Buy |
Arctom | AS426912 | Ivabradine hydrochloride ≥98% | 50mg | $9 | 2021-12-16 | Buy |
Arctom | AS426912 | Ivabradine hydrochloride ≥98% | 100mg | $16 | 2021-12-16 | Buy |
Arctom | AS426912 | Ivabradine hydrochloride ≥98% | 250mg | $29 | 2021-12-16 | Buy |
Arctom | AS426912 | Ivabradine hydrochloride ≥98% | 1g | $75 | 2021-12-16 | Buy |
Arctom | AS426912 | Ivabradine hydrochloride ≥98% | 5g | $276 | 2021-12-16 | Buy |
Properties
Melting point :193-196?C
alpha :58921 +7.8°; 36521 +27.8° (c = 1% in DMSO)
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL (warmed)
form :powder
color :white to beige
optical activity :[α]/D +5 to +9°, c = 1 in DMSO
Merck :14,5247
InChIKey :HLUKNZUABFFNQS-ZMBIFBSDSA-N
SMILES :C([C@H]1CC2=CC(OC)=C(OC)C=C12)N(C)CCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl |&1:1,r|
CAS DataBase Reference :148849-67-6(CAS DataBase Reference)
alpha :58921 +7.8°; 36521 +27.8° (c = 1% in DMSO)
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL (warmed)
form :powder
color :white to beige
optical activity :[α]/D +5 to +9°, c = 1 in DMSO
Merck :14,5247
InChIKey :HLUKNZUABFFNQS-ZMBIFBSDSA-N
SMILES :C([C@H]1CC2=CC(OC)=C(OC)C=C12)N(C)CCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl |&1:1,r|
CAS DataBase Reference :148849-67-6(CAS DataBase Reference)
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Ivabradine is a highly selective open channel blocker that targets the mixed Na+/K+ inward “funny current” (If) carried by hyperpolarization-activated cyclic nucleotide gated (HCN) channels. It suppresses channel activity at HCN1, HCN2, and HCN4, all with the same EC50 value of 4 μM. Notably, ivabradine selectively targets cardiac signaling, resulting in resting heart rate reducing (bradycardic) effects.More related product prices
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Suppliers and manufacturers
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