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ChemicalBook >> CAS DataBase List >> HC TOXIN

HC TOXIN

HC TOXIN price.
  • $97 - $1540
  • Product name: HC TOXIN
  • CAS: 83209-65-8
  • MF: C21H32N4O6
  • MW: 436.51
  • EINECS:
  • MDL Number:MFCD29924706
  • Synonyms:HC TOXIN FROM HELMINTHOSPORIUM CARBONUM;Cyclo[D-Pro-L-Ala-D-Ala-2-(6-oxo-6-oxiranylhexyl)-L-Gly-];Cyclo[L-Ala-D-Ala-[(2S)-2-amino*-8-oxo-8-oxiranyloctanoyl]-D-Pro-];HC toxin I;Toxin I;Cyclic(L-alanyl-D-alanyl-eta-oxo-L-alpha-aminooxiraneoctanoyl-D-prolyl);Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine);Cyclo(aoe-Pro-Ala-ala)
6 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number1785AH
  • Product descriptionHCToxin
  • Packaging1mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10576
  • Product descriptionHC Toxin ≥95%
  • Packaging500μg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10576
  • Product descriptionHC Toxin ≥95%
  • Packaging1mg
  • Price$165
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10576
  • Product descriptionHC Toxin ≥95%
  • Packaging5mg
  • Price$721
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberH7270
  • Product descriptionHC toxin from Helminthosporium carbonum lyophilized powder
  • Packaging5mg
  • Price$767
  • Updated2022-05-15
  • Buy
  • ManufacturerTRC
  • Product numberH115005
  • Product descriptionHCToxin
  • Packaging5mg
  • Price$1540
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1785AH HCToxin 1mg $280 2021-12-16 Buy
Cayman Chemical 10576 HC Toxin ≥95% 500μg $97 2024-03-01 Buy
Cayman Chemical 10576 HC Toxin ≥95% 1mg $165 2024-03-01 Buy
Cayman Chemical 10576 HC Toxin ≥95% 5mg $721 2024-03-01 Buy
Sigma-Aldrich H7270 HC toxin from Helminthosporium carbonum lyophilized powder 5mg $767 2022-05-15 Buy
TRC H115005 HCToxin 5mg $1540 2021-12-16 Buy

Properties

Boiling point :819.2±65.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 10 mg/ml; Methanol: 10 mg/ml
pka :13.33±0.70(Predicted)
form :lyophilized powder
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC50 = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.

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