BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE
- $44 - $710
- Product name: BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE
- CAS: 200626-61-5
- MF: C13H7Cl2N3O
- MW: 292.12
- EINECS:
- MDL Number:MFCD00195103
- Synonyms:IFLAB-BB F0451-3184;BENZOTRIAZOL-1-YL-(2,4-DICHLORO-PHENYL)-METHANONE;1-(2,4-Dichlorobenzoyl)-1H-benzotriazole;ITSA-1(ITSA1);CS-2249;Methanone, 1H-benzotriazol-1-yl(2,4-dichlorophenyl)-;(1H-Benzo[d][1,2,3]triazol-1-yl)(2,4-dichlorophenyl)methanone;inhibit,Histone deacetylases,ITSA-1,Inhibitor,HDAC,ITSA 1
23 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number9078BA
- Product descriptionN-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide
- Packaging100mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA879167
- Product descriptionITSA-1 99+%
- Packaging10mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA879167
- Product descriptionITSA-1 99+%
- Packaging25mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA879167
- Product descriptionITSA-1 99+%
- Packaging50mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA879167
- Product descriptionITSA-1 99+%
- Packaging100mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA879167
- Product descriptionITSA-1 99+%
- Packaging250mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA879167
- Product descriptionITSA-1 99+%
- Packaging1g
- Price$710
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7816
- Product descriptionITSA-1(ITSA1)
- Packaging10mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7816
- Product descriptionITSA-1(ITSA1)
- Packaging25mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7816
- Product descriptionITSA-1(ITSA1)
- Packaging50mg
- Price$205
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7816
- Product descriptionITSA-1(ITSA1)
- Packaging100mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18681
- Product descriptionITSA1 ≥95%
- Packaging100mg
- Price$257
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18681
- Product descriptionITSA1 ≥95%
- Packaging50mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18681
- Product descriptionITSA1 ≥95%
- Packaging25mg
- Price$92
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18681
- Product descriptionITSA1 ≥95%
- Packaging10mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5854
- Product descriptionITSA-1 >98.0%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 9078BA | N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide | 100mg | $147 | 2021-12-16 | Buy |
Ambeed | A879167 | ITSA-1 99+% | 10mg | $44 | 2021-12-16 | Buy |
Ambeed | A879167 | ITSA-1 99+% | 25mg | $59 | 2021-12-16 | Buy |
Ambeed | A879167 | ITSA-1 99+% | 50mg | $76 | 2021-12-16 | Buy |
Ambeed | A879167 | ITSA-1 99+% | 100mg | $98 | 2021-12-16 | Buy |
Ambeed | A879167 | ITSA-1 99+% | 250mg | $146 | 2021-12-16 | Buy |
Ambeed | A879167 | ITSA-1 99+% | 1g | $710 | 2021-12-16 | Buy |
ApexBio Technology | B7816 | ITSA-1(ITSA1) | 10mg | $79 | 2021-12-16 | Buy |
ApexBio Technology | B7816 | ITSA-1(ITSA1) | 25mg | $134 | 2021-12-16 | Buy |
ApexBio Technology | B7816 | ITSA-1(ITSA1) | 50mg | $205 | 2021-12-16 | Buy |
ApexBio Technology | B7816 | ITSA-1(ITSA1) | 100mg | $347 | 2021-12-16 | Buy |
Cayman Chemical | 18681 | ITSA1 ≥95% | 100mg | $257 | 2024-03-01 | Buy |
Cayman Chemical | 18681 | ITSA1 ≥95% | 50mg | $161 | 2024-03-01 | Buy |
Cayman Chemical | 18681 | ITSA1 ≥95% | 25mg | $92 | 2024-03-01 | Buy |
Cayman Chemical | 18681 | ITSA1 ≥95% | 10mg | $44 | 2024-03-01 | Buy |
ChemScene | CS-5854 | ITSA-1 >98.0% | 10mg | $60 | 2021-12-16 | Buy |
Properties
Melting point :119-121°C
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: ~28mg/mL
form :solid
color :White to Off-White
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: ~28mg/mL
form :solid
color :White to Off-White
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Trichostatin A (TSA; ) is a potent, reversible inhibitor of histone deacetylase (HDAC) that inhibits HDAC1 (IC50 = 70 nM) in Jurkat cells, resulting in cell cycle arrest. ITSA1 is a cell-permeable benzotriazole amide that blocks TSA action, reducing TSA-induced acetylation of histone and tubulin in A549 cells when given at 50 μM. At the same concentration, ITSA1 also prevents TSA-mediated cell cycle arrest and apoptosis. It similarly blocks the action of the HDAC inhibitor SAHA , preventing SAHA-induced hyperacetylation of tubulin in A549 cells. ITSA1 reduces TSA-regulated transcription in mouse embryonic stem cells and in zebrafish.More related product prices
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