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ChemicalBook >> CAS DataBase List >> GSK 2330672

GSK 2330672

GSK 2330672 price.
  • $110 - $3900
  • Product name: GSK 2330672
  • CAS: 1345982-69-5
  • MF: C28H38N2O7S
  • MW: 546.68
  • EINECS:604-604-1
  • MDL Number:MFCD28386358
  • Synonyms:GSK 2330672;GSK 2330672; GSK-2330672;3-[[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-4,5-dihydro-2H-1λ6,4-benzothiazepin-8-yl]methylamino]pentanedioic acid;Pentanedioic acid, 3-((((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl)methyl)amino)-;CS-2639;Iinerixibat;Iinerixibat (GSK2330672);linerixibat
10 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4578DL
  • Product descriptionLinerixibat
  • Packaging5mg
  • Price$671
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23843
  • Product descriptionGSK2330672 ≥98%
  • Packaging1mg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23843
  • Product descriptionGSK2330672 ≥98%
  • Packaging5mg
  • Price$515
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23843
  • Product descriptionGSK2330672 ≥98%
  • Packaging10mg
  • Price$918
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003808
  • Product descriptionGSK2330672 98+%
  • Packaging100mg
  • Price$1459
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003808
  • Product descriptionGSK2330672 98+%
  • Packaging50mg
  • Price$1042
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003808
  • Product descriptionGSK2330672 98+%
  • Packaging10mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003808
  • Product descriptionGSK2330672 98+%
  • Packaging5mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9712
  • Product descriptionIinerixibat >98%
  • Packaging1g
  • Price$3900
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9712
  • Product descriptionIinerixibat >98%
  • Packaging250mg
  • Price$1900
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4578DL Linerixibat 5mg $671 2021-12-16 Buy
Cayman Chemical 23843 GSK2330672 ≥98% 1mg $110 2024-03-01 Buy
Cayman Chemical 23843 GSK2330672 ≥98% 5mg $515 2024-03-01 Buy
Cayman Chemical 23843 GSK2330672 ≥98% 10mg $918 2024-03-01 Buy
Crysdot CD31003808 GSK2330672 98+% 100mg $1459 2021-12-16 Buy
Crysdot CD31003808 GSK2330672 98+% 50mg $1042 2021-12-16 Buy
Crysdot CD31003808 GSK2330672 98+% 10mg $347 2021-12-16 Buy
Crysdot CD31003808 GSK2330672 98+% 5mg $208 2021-12-16 Buy
DC Chemicals DC9712 Iinerixibat >98% 1g $3900 2021-12-16 Buy
DC Chemicals DC9712 Iinerixibat >98% 250mg $1900 2021-12-16 Buy

Properties

Boiling point :730.8±60.0 °C(Predicted)
Density :1.218±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 5 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form :A crystalline solid
pka :3.27±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GSK2330672 is an inhibitor of the apical sodium-dependent bile acid transporter (ASBT; IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total GLP-1 and plasma insulin in Zucker diabetic fatty (ZDF) rats.

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