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ChemicalBook >> CAS DataBase List >> Estradiol

Estradiol

Estradiol price.
  • $35 - $811
  • Product name: Estradiol
  • CAS: 57-91-0
  • MF: C18H24O2
  • MW: 272.39
  • EINECS:200-354-8
  • MDL Number:MFCD00064144
  • Synonyms:1,3,5-estratriene-3,17-alpha-diol ;1,3,5-Estratriene-3,17alpha-diol;17alpha-Oestradiol;3,17alpha-Dihydroxyestra-1,3,5(10)-triene;3,17-alpha-dihydroxyoestra-1,3,5(10)-triene ;3,17alpha-Dihydroxyoestra-1,3,5(10)-triene;5(10)-triene-3,17-diol,(17-alpha)-estra-3 ;epiestradial
26 prices
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Brand
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 100
  • 50mg
  • 25mg
  • 50
  • 10mM(in 1mL Ethanol)
  • 100mg
  • 500ul
  • 500mg
  • 1g
  • 5g
  • 48Tests
  • ManufacturerApexBio Technology
  • Product numberB7201
  • Product descriptionα-Estradiol
  • Packaging50mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7201
  • Product descriptionα-Estradiol
  • Packaging10mM(in 1mL Ethanol)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20776
  • Product description17α-Estradiol ≥98%
  • Packaging50mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20776
  • Product description17α-Estradiol ≥98%
  • Packaging100mg
  • Price$76
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20776
  • Product description17α-Estradiol ≥98%
  • Packaging500mg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20776
  • Product description17α-Estradiol ≥98%
  • Packaging1g
  • Price$195
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014231
  • Product descriptionAlpha-Estradiol 99.77%
  • Packaging100mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0014231
  • Product descriptionAlpha-Estradiol 99.77%
  • Packaging500mg
  • Price$100
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD32000922
  • Product description17α-Estradiol 95+%
  • Packaging1g
  • Price$273
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN17211
  • Product descriptionα-Estradiol
  • Packaging25mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN17211
  • Product descriptionα-Estradiol
  • Packaging100mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerLabseeker
  • Product numberSC-81163
  • Product description17α-Estradiol 98
  • Packaging5g
  • Price$354
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number70017
  • Product description17α-Estradiol
  • Packaging50mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberE8750
  • Product descriptionα-Estradiol powder, ≥98% (TLC)
  • Packaging100mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number46542
  • Product descriptionα-Estradiol VETRANAL
  • Packaging100mg
  • Price$156
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberE8750
  • Product descriptionα-Estradiol powder, ≥98% (TLC)
  • Packaging500mg
  • Price$273
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7201 α-Estradiol 50mg $45 2021-12-16 Buy
ApexBio Technology B7201 α-Estradiol 10mM(in 1mL Ethanol) $50 2021-12-16 Buy
Cayman Chemical 20776 17α-Estradiol ≥98% 50mg $40 2024-03-01 Buy
Cayman Chemical 20776 17α-Estradiol ≥98% 100mg $76 2024-03-01 Buy
Cayman Chemical 20776 17α-Estradiol ≥98% 500mg $138 2024-03-01 Buy
Cayman Chemical 20776 17α-Estradiol ≥98% 1g $195 2024-03-01 Buy
ChemScene CS-0014231 Alpha-Estradiol 99.77% 100mg $60 2021-12-16 Buy
ChemScene CS-0014231 Alpha-Estradiol 99.77% 500mg $100 2021-12-16 Buy
Crysdot CD32000922 17α-Estradiol 95+% 1g $273 2021-12-16 Buy
CSNpharm CSN17211 α-Estradiol 25mg $35 2021-12-16 Buy
CSNpharm CSN17211 α-Estradiol 100mg $48 2021-12-16 Buy
Labseeker SC-81163 17α-Estradiol 98 5g $354 2021-12-16 Buy
Medical Isotopes, Inc. 70017 17α-Estradiol 50mg $90 2021-12-16 Buy
Sigma-Aldrich E8750 α-Estradiol powder, ≥98% (TLC) 100mg $120 2024-03-01 Buy
Sigma-Aldrich 46542 α-Estradiol VETRANAL 100mg $156 2024-03-01 Buy
Sigma-Aldrich E8750 α-Estradiol powder, ≥98% (TLC) 500mg $273 2024-03-01 Buy

Properties

Melting point :176-180 °C(lit.)
Boiling point :355.44°C (rough estimate)
alpha :D20 +53 to +56° (c = 0.9 in dioxane)
Density :1.0708 (rough estimate)
refractive index :1.4800 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :ethanol: 50 mg/mL, clear, colorless
form :powder
pka :10.27±0.60(Predicted)
color :white with slight yellow
Water Solubility :3.9mg/L(25 ºC)
Merck :14,3704
CAS DataBase Reference :57-91-0(CAS DataBase Reference)
NIST Chemistry Reference :Estra-1,3,5(10)-triene-3,17alpha-diol(57-91-0)
EPA Substance Registry System :Estra-1,3,5(10)-triene-3,17-diol, (17.alpha.)- (57-91-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P273 Avoid release to the environment.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

α-Estradiol is an endogenous ligand for estrogen receptors ERα (Ki = 0.2 nM) and ERβ (Ki = 1.2 nM). Studies indicate that α-Estradiol is a short acting estrogen which only forms complexes with estrogen ligand receptors for a short period of time. These studies suggest that α-estradiol is beneficial in studying the affects caused by the MAPK signaling cascade such as cell division, neuronal differentiation, and neuronal survival in the developing brain. Furthermore, α-estradiol inhibits the influx of calcium in human aortic smooth muscle cells.

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