Diosmetin
- $5 - $770
- Product name: Diosmetin
- CAS: 520-34-3
- MF: C16H12O6
- MW: 300.26
- EINECS:208-291-8
- MDL Number:MFCD00017425
- Synonyms:3',5,7-TRIHYDROXY-4'METHOXYFLAVONE;4'-METHOXY-5,7,3'-TRIHYDROXYFLAVONE;4-METHOXY-5,7,3'-TRIHYDROXYFLAVONE;5,7,3'-TRIHYDROXY-4'-METHOXYFLAVONE;DIOSMETIN;5,7-Dihydroxy-2-[3-hydroxy-4-methoxyphenyl]-[4H]-1-benzopyran-4-one;4'-Methylluteolin;Diosmetol
48 prices
Selected condition:
Brand
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100MG
- 200mg
- 250mg
- 500mg
- 1000mg
- 1g
- 2g
- 5g
- 10g
- 50g
- 100g
- 25g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberAPI-1501
- Product descriptionDiosmetin 98%
- Packaging25g
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ51310
- Product descriptionDiosmetin
- Packaging1g
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124051
- Product descriptionDiosmetin 96%
- Packaging5g
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124051
- Product descriptionDiosmetin 96%
- Packaging10g
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124051
- Product descriptionDiosmetin 96%
- Packaging25g
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0005231
- Product descriptionDIOSMETIN 95.00%
- Packaging100MG
- Price$202.65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5990
- Product descriptionDiosmetin
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS014529
- Product descriptionDiosmetin 96%
- Packaging100mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS014529
- Product descriptionDiosmetin 96%
- Packaging250mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS014529
- Product descriptionDiosmetin 96%
- Packaging1g
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS014529
- Product descriptionDiosmetin 96%
- Packaging5g
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN90210
- Product descriptionDiosmetin ≥98%
- Packaging20mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS014529
- Product descriptionDiosmetin 96%
- Packaging10g
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS014529
- Product descriptionDiosmetin 96%
- Packaging25g
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY066981
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one ≥95%
- Packaging100g
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2729
- Product descriptionDiosmetin
- Packaging1g
- Price$149
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | API-1501 | Diosmetin 98% | 25g | $750 | 2021-12-16 | Buy |
AK Scientific | J51310 | Diosmetin | 1g | $117 | 2021-12-16 | Buy |
Ambeed | A124051 | Diosmetin 96% | 5g | $32 | 2021-12-16 | Buy |
Ambeed | A124051 | Diosmetin 96% | 10g | $53 | 2021-12-16 | Buy |
Ambeed | A124051 | Diosmetin 96% | 25g | $104 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0005231 | DIOSMETIN 95.00% | 100MG | $202.65 | 2021-12-16 | Buy |
ApexBio Technology | B5990 | Diosmetin | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
Arctom | AS014529 | Diosmetin 96% | 100mg | $5 | 2021-12-16 | Buy |
Arctom | AS014529 | Diosmetin 96% | 250mg | $8 | 2021-12-16 | Buy |
Arctom | AS014529 | Diosmetin 96% | 1g | $13 | 2021-12-16 | Buy |
Arctom | AS014529 | Diosmetin 96% | 5g | $32 | 2021-12-16 | Buy |
Arctom | CFN90210 | Diosmetin ≥98% | 20mg | $50 | 2021-12-16 | Buy |
Arctom | AS014529 | Diosmetin 96% | 10g | $52 | 2021-12-16 | Buy |
Arctom | AS014529 | Diosmetin 96% | 25g | $103 | 2021-12-16 | Buy |
Arctom | SY066981 | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one ≥95% | 100g | $270 | 2021-12-16 | Buy |
AvaChem | 2729 | Diosmetin | 1g | $149 | 2021-12-16 | Buy |
Properties
Melting point :256-258°C
Boiling point :576.7±50.0 °C(Predicted)
Density :1.512±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in acetonitrile, DMSO (60 mg/ml), and ethanol (17 mg/ml), clear, light yellow to yellow.
form :Solid
pka :6.50±0.40(Predicted)
color :light yellow to yellow
Water Solubility :19μg/L at 20℃
BRN :294492
Stability :Hygroscopic
InChIKey :MBNGWHIJMBWFHU-UHFFFAOYSA-N
LogP :3.1 at 20℃
CAS DataBase Reference :520-34-3(CAS DataBase Reference)
Boiling point :576.7±50.0 °C(Predicted)
Density :1.512±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in acetonitrile, DMSO (60 mg/ml), and ethanol (17 mg/ml), clear, light yellow to yellow.
form :Solid
pka :6.50±0.40(Predicted)
color :light yellow to yellow
Water Solubility :19μg/L at 20℃
BRN :294492
Stability :Hygroscopic
InChIKey :MBNGWHIJMBWFHU-UHFFFAOYSA-N
LogP :3.1 at 20℃
CAS DataBase Reference :520-34-3(CAS DataBase Reference)
Safety Information
Symbol(GHS): | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||
Hazard statements: |
|
||||||||||||||
Precautionary statements: |
|
Description
Diosmetin is a natural O-methylated flavone that is structurally related to luteolin . It reversibly inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes with Ki values of 89 and 16 nM, respectively. It less potently inhibits CYP2C8 and CYP2C9 (Kis = 3.1 and 1.7 μM, respectively). While diosmetin inhibits CYP1A1 activity, it increases the transcription of the CYP1A1 gene in MCF-7 cells by activating the aryl hydrocarbon receptor when applied at 5 μM. Diosmetin also inhibits signaling through the stem cell factor receptor, c-Kit, at micromolar concentrations.Related product price
- Luteolin
$5-1250 - Coumarin 6
$24-807 - Coumarin-3-carboxylic acid
$5-1068.61
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.