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ChemicalBook >> CAS DataBase List >> DAPH

DAPH

DAPH price.
  • $49 - $823
  • Product name: DAPH
  • CAS: 145915-58-8
  • MF: C20H15N3O2
  • MW: 329.35
  • EINECS:406-050-3
  • MDL Number:MFCD00236442
  • Synonyms:DAPH/CGP 52411;4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411;DAPH-1 (DAPH;1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-;DAPH >=98% (HPLC), solid
13 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number0212CA
  • Product description4,5-Dianilinophthalimide
  • Packaging5mg
  • Price$271
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0212CA
  • Product description4,5-Dianilinophthalimide
  • Packaging25mg
  • Price$823
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7384
  • Product descriptionCGP52411
  • Packaging10mg
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29196
  • Product descriptionDAPH
  • Packaging1mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29196
  • Product descriptionDAPH
  • Packaging5mg
  • Price$156
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29196
  • Product descriptionDAPH
  • Packaging10mg
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29196
  • Product descriptionDAPH
  • Packaging25mg
  • Price$651
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0027891
  • Product descriptionCGP52411 99.82%
  • Packaging5mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN25283
  • Product descriptionCGP?52411
  • Packaging5mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN25283
  • Product descriptionCGP?52411
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD3943
  • Product descriptionDAPH ≥98% (HPLC), solid
  • Packaging5mg
  • Price$198
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD3943
  • Product descriptionDAPH ≥98% (HPLC), solid
  • Packaging25mg
  • Price$630
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC583570
  • Product descriptionCGP52411
  • Packaging5mg
  • Price$300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0212CA 4,5-Dianilinophthalimide 5mg $271 2021-12-16 Buy
AK Scientific 0212CA 4,5-Dianilinophthalimide 25mg $823 2021-12-16 Buy
ApexBio Technology B7384 CGP52411 10mg $282 2021-12-16 Buy
Cayman Chemical 29196 DAPH 1mg $49 2024-03-01 Buy
Cayman Chemical 29196 DAPH 5mg $156 2024-03-01 Buy
Cayman Chemical 29196 DAPH 10mg $286 2024-03-01 Buy
Cayman Chemical 29196 DAPH 25mg $651 2024-03-01 Buy
ChemScene CS-0027891 CGP52411 99.82% 5mg $660 2021-12-16 Buy
CSNpharm CSN25283 CGP?52411 5mg $53 2021-12-16 Buy
CSNpharm CSN25283 CGP?52411 10mg $90 2021-12-16 Buy
Sigma-Aldrich D3943 DAPH ≥98% (HPLC), solid 5mg $198 2024-03-01 Buy
Sigma-Aldrich D3943 DAPH ≥98% (HPLC), solid 25mg $630 2024-03-01 Buy
TRC C583570 CGP52411 5mg $300 2021-12-16 Buy

Properties

Melting point :199-202℃
Density :1.374
storage temp. :2-8°C
solubility :DMSO: ~30 mg/mL
pka :9.06±0.20(Predicted)
form :solid
color :orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
Precautionary statements:
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

DAPH is a tyrosine kinase inhibitor, which suppresses and reverses the formation of Aβ42 fibers in neurons. DAPH displays specificity towards the EGFR kinase3 receptor. Studies suggest that DAPH can attenuate phenylephrine-induced endothelium contraction in aortic rings. It is known that Aβ42 proteins are composed of β sheets that are arranged parallel to the fibril axis and are several micrometers in length. DAPH is a useful tool in inhibiting these proteins because it can disrupt fibril formation which is vital for β sheet formation.

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