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ChemicalBook >> CAS DataBase List >> COCHLIOQUINONE A

COCHLIOQUINONE A

COCHLIOQUINONE A price.
  • $245 - $1390
  • Product name: COCHLIOQUINONE A
  • CAS: 32450-25-2
  • MF: C30H44O8
  • MW: 532.67
  • EINECS:
  • MDL Number:MFCD08062299
  • Synonyms:COCHLIOQUINONE A;(3R)-9-[(1S,2R,3S)-2-Acetyloxy-1,3-dimethylpentyl]-1,2,3,4aβ,5,6,6a,12,12aβ,12b-decahydro-12β-hydroxy-3α-(1-hydroxy-1-methylethyl)-6aα,12bα-dimethylpyrano[3,2-a]xanthene-8,11-dione;Luteoleersin;Cochlioquinone;Pyrano[3,2-a]xanthene-8,11-dione, 9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy-3-(1-hydroxy-1-methylethyl)-6a,12b-dimethyl-, (3R,4aR,6aR,12S,12aS,12bR)-;Coclioquinone A;(2S,3R,4S)-2-[(3R,4aR,6aR,12S,12bR)-12-hydroxy-3-(2-hydroxypropan-2-yl)-6a,12b-dimethyl-8,11-dioxo-1,2,3,4a,5,6,12,12a-octahydropyrano[3,2-a]xanthen-9-yl]-4-methylhexan-3-yl] acetate
5 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 500μg
  • 2.5mg
  • 5MG
  • ManufacturerAK Scientific
  • Product number1051CB
  • Product descriptionCochlioquinoneA
  • Packaging2.5mg
  • Price$1390
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberMTB0000899
  • Product descriptionCOCHLIOQUINONE-A 95.00%
  • Packaging5MG
  • Price$497.63
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19440
  • Product descriptionCochlioquinone A ≥99%
  • Packaging500μg
  • Price$291
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19440
  • Product descriptionCochlioquinone A ≥99%
  • Packaging2.5mg
  • Price$1160
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC633560
  • Product descriptionCochlioquinoneA
  • Packaging500μg
  • Price$245
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1051CB CochlioquinoneA 2.5mg $1390 2021-12-16 Buy
American Custom Chemicals Corporation MTB0000899 COCHLIOQUINONE-A 95.00% 5MG $497.63 2021-12-16 Buy
Cayman Chemical 19440 Cochlioquinone A ≥99% 500μg $291 2024-03-01 Buy
Cayman Chemical 19440 Cochlioquinone A ≥99% 2.5mg $1160 2024-03-01 Buy
TRC C633560 CochlioquinoneA 500μg $245 2021-12-16 Buy

Properties

Melting point :135 °C
Boiling point :638.8±55.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form :A yellow lyophilisate
pka :11.57±0.70(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK; Ki = 3.1 μM) and diacylglycerol acyltransferase (DGAT; IC50 = 5.6 μM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 μM. It is also reported to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors with an IC50 value of 11 μM.

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