Aristolochic acid
- $32 - $1732.5
- Product name: Aristolochic acid
- CAS: 313-67-7
- MF: C17H11NO7
- MW: 341.27
- EINECS:206-238-3
- MDL Number:MFCD00004996
- Synonyms:Aristolochic acid, mixture of I and II, 96%;8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic Acid;Aristolochia A;Aristolochic Acid 1;NSC 11926;TR 1736;Aristolochic;Aristolochic acid (93% of Aristolochic acid I)
36 prices
Selected condition:
Brand
- AHH
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- JR MediChem
- Sigma-Aldrich
- TRC
Package
- y0001185
- 10mg
- 20mg
- 25MG
- 50mg
- 100mg
- 250MG
- y0001323
- 1g
- ManufacturerAHH
- Product numberMT-47223
- Product descriptionAristolochicacid 97%
- Packaging1g
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA714436
- Product descriptionAristolochicAcidA 99+%
- Packaging100mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000398
- Product descriptionARISTOLOCHIC ACID A 95.00%
- Packaging250MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0000398
- Product descriptionARISTOLOCHIC ACID A 95.00%
- Packaging25MG
- Price$180.6
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2032
- Product descriptionAristolochicAcidA
- Packaging20mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY074862
- Product descriptionAristolochicacidI,95% ≥98%
- Packaging10mg
- Price$95.45
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS643278
- Product descriptionAristolochicAcidA ≥99%
- Packaging100mg
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN99505
- Product descriptionAristolochicacidA ≥98%
- Packaging20mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1871
- Product descriptionAristolochic acid I
- Packaging100mg
- Price$249
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545885
- Product descriptionAristolochic acid >98%
- Packaging20mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545885
- Product descriptionAristolochic acid >98%
- Packaging100mg
- Price$389.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105211
- Product descriptionAristolochic acid >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA17982
- Product descriptionAristolochic acid - Mixture of I and II
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA17982
- Product descriptionAristolochic acid - Mixture of I and II
- Packaging25mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberXA167153
- Product descriptionAristolochic acid I
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberXA167153
- Product descriptionAristolochic acid I
- Packaging25mg
- Price$175
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-47223 | Aristolochicacid 97% | 1g | $430 | 2021-12-16 | Buy |
Ambeed | A714436 | AristolochicAcidA 99+% | 100mg | $98 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0000398 | ARISTOLOCHIC ACID A 95.00% | 250MG | $1732.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0000398 | ARISTOLOCHIC ACID A 95.00% | 25MG | $180.6 | 2021-12-16 | Buy |
ApexBio Technology | N2032 | AristolochicAcidA | 20mg | $80 | 2021-12-16 | Buy |
Arctom | SY074862 | AristolochicacidI,95% ≥98% | 10mg | $95.45 | 2021-12-16 | Buy |
Arctom | AS643278 | AristolochicAcidA ≥99% | 100mg | $97 | 2021-12-16 | Buy |
Arctom | CFN99505 | AristolochicacidA ≥98% | 20mg | $100 | 2021-12-16 | Buy |
AvaChem | 1871 | Aristolochic acid I | 100mg | $249 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545885 | Aristolochic acid >98% | 20mg | $154.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545885 | Aristolochic acid >98% | 100mg | $389.3 | 2021-12-16 | Buy |
Biorbyt Ltd | orb105211 | Aristolochic acid >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA17982 | Aristolochic acid - Mixture of I and II | 10mg | $60 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA17982 | Aristolochic acid - Mixture of I and II | 25mg | $120 | 2021-12-16 | Buy |
Biosynth Carbosynth | XA167153 | Aristolochic acid I | 10mg | $125 | 2021-12-16 | Buy |
Biosynth Carbosynth | XA167153 | Aristolochic acid I | 25mg | $175 | 2021-12-16 | Buy |
Properties
Melting point :260 °C
Boiling point :476.92°C (rough estimate)
Density :1.3162 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
pka :2.99±0.20(Predicted)
form :powder
color :yellow
InChIKey :LIDQMWRBMLSXLL-UHFFFAOYSA-N
CAS DataBase Reference :313-67-7(CAS DataBase Reference)
IARC :1 (Vol. 82, 100A) 2012, 1 (Vol. 82, 100A) 2012
Boiling point :476.92°C (rough estimate)
Density :1.3162 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
pka :2.99±0.20(Predicted)
form :powder
color :yellow
InChIKey :LIDQMWRBMLSXLL-UHFFFAOYSA-N
CAS DataBase Reference :313-67-7(CAS DataBase Reference)
IARC :1 (Vol. 82, 100A) 2012, 1 (Vol. 82, 100A) 2012
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
Aristolochic Acid is an alkaloid that was originally derived from Aristolochia radix. This compound is a potent PLA2 enzyme inhibitor and also suppresses edema-inducing activity as well as direct and indirect hemolytic activity. Specifically, Aristolochic Acid displays anti-inflammatory activity against edema in mouse foot pads induced by PLA2. Other experiments have shown this agent to be associated with aristolochic acid nephropathy. Mechanistic studies have reported Aristolochic Acid to play a regulatory role towards genes in DNA repair processes and responses to DNA damage stimulus, regulation of cell cycle, and apoptosis. More detailed studies have shown this compound to up-regulate GADD 45β, NAIP genes and down-regulate TP53, PARP1, ERCC1, OGG1/2, MGMT, and ERCC2 genes. Furthermore, a down-regulation of gene expression in anti-oxidant enzymes was also observed by Aristolochic Acid treatment of human kidney tubular cells. These studies suggest that oxidative stress plays a role in the cytotoxicity of Aristolochic Acid.Related product price
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