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ChemicalBook >> CAS DataBase List >> Abacavir 5’-Phosphate

Abacavir 5’-Phosphate

Abacavir 5’-Phosphate price.
  • $90 - $1911
  • Product name: Abacavir 5’-Phosphate
  • CAS: 136470-77-4
  • MF: C14H19N6O4P
  • MW: 366.31
  • EINECS:
  • MDL Number:MFCD23160255
  • Synonyms:Abacavir 5’-Phosphate;(1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester);(1S-cis)-Abacavir Monophosphate;[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate;((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)-;Abacavir Impurity 13;Abacavir 5'-Phosphate
8 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number3389CC
  • Product descriptionAbacavir5'-phosphate
  • Packaging5mg
  • Price$1468
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberMTB0000817
  • Product descriptionABACAVIR-5-PHOSPHATE 95.00%
  • Packaging5MG
  • Price$500.29
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA16495
  • Product descriptionAbacavir 5'-phosphate
  • Packaging1mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA16495
  • Product descriptionAbacavir 5'-phosphate
  • Packaging2mg
  • Price$578.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA16495
  • Product descriptionAbacavir 5'-phosphate
  • Packaging5mg
  • Price$1051.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberNA16495
  • Product descriptionAbacavir 5'-phosphate
  • Packaging10mg
  • Price$1911
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA105020
  • Product descriptionAbacavir5’-Phosphate
  • Packaging1mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA105020
  • Product descriptionAbacavir5’-Phosphate
  • Packaging10mg
  • Price$625
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3389CC Abacavir5'-phosphate 5mg $1468 2021-12-16 Buy
American Custom Chemicals Corporation MTB0000817 ABACAVIR-5-PHOSPHATE 95.00% 5MG $500.29 2021-12-16 Buy
Biosynth Carbosynth NA16495 Abacavir 5'-phosphate 1mg $318 2021-12-16 Buy
Biosynth Carbosynth NA16495 Abacavir 5'-phosphate 2mg $578.1 2021-12-16 Buy
Biosynth Carbosynth NA16495 Abacavir 5'-phosphate 5mg $1051.1 2021-12-16 Buy
Biosynth Carbosynth NA16495 Abacavir 5'-phosphate 10mg $1911 2021-12-16 Buy
TRC A105020 Abacavir5’-Phosphate 1mg $90 2021-12-16 Buy
TRC A105020 Abacavir5’-Phosphate 10mg $625 2021-12-16 Buy

Properties

Melting point :189-194°C (dec.)
Boiling point :749.3±70.0 °C(Predicted)
Density :1.93±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Methanol, Water
pka :1.91±0.10(Predicted)
form :Solid
color :White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

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