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ChemicalBook >> CAS DataBase List >> AC480 (BMS-599626)

AC480 (BMS-599626)

AC480 (BMS-599626) price.
  • $36 - $1291
  • Product name: AC480 (BMS-599626)
  • CAS: 714971-09-2
  • MF: C27H27FN8O3
  • MW: 530.55
  • EINECS:
  • MDL Number:MFCD10565678
  • Synonyms:Carbamic acid, [4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester (9CI);AC-480;N-[4-[[1-[(3-Fluorophenyl)Methyl]-1H-indazol-5-yl]aMino]-5-Methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbaMic Acid (3S)-3-MorpholinylMethyl Ester;(S)-Morpholin-3-ylmethyl (4-((1-(3-fluorobenzyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo[2,1-f][1,;AC480 (BMS-599626);(S)-morpholin-3-ylmethyl 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-ylcarbamate;(3S)-morpholin-3-ylmethyl N-[4-({1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}amino)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate;[(3S)-Morpholin-3-yl]methyl N-[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-5-methyl-pyrrolo
20 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chem-Impex
  • Crysdot
  • DC Chemicals
  • TCI Chemical
  • TRC
Package
  • 10mg
  • 25mg
  • 50MG
  • 250mg
  • 1mg
  • 5mg
  • 100mg
  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1142-M001
  • Product descriptionBMS-599626 ≥95%
  • Packaging1mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1142-M100
  • Product descriptionBMS-599626 ≥95%
  • Packaging100mg
  • Price$1291
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1142
  • Product descriptionBMS-599626
  • Packaging5mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0045911
  • Product description(S)-MORPHOLIN-3-YLMETHYL 4-(1- (3-FLUOROBENZYL)-1H-INDAZOL-5-YLAMINO) -5-METHYLPYRROLO[1,2-F][1,2,4] TRIAZIN-6-YLCARBAMATE 95.00%
  • Packaging5MG
  • Price$499.6
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2822
  • Product descriptionAC480(BMS-599626)
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2822
  • Product descriptionAC480(BMS-599626)
  • Packaging10mM(in 1mL DMSO)
  • Price$273
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2822
  • Product descriptionAC480(BMS-599626)
  • Packaging25mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2822
  • Product descriptionAC480(BMS-599626)
  • Packaging100mg
  • Price$840
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29657
  • Product descriptionAC480
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29657
  • Product descriptionAC480
  • Packaging5mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29657
  • Product descriptionAC480
  • Packaging10mg
  • Price$223
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29657
  • Product descriptionAC480
  • Packaging25mg
  • Price$510
  • Updated2024-03-01
  • Buy
  • ManufacturerChem-Impex
  • Product number37687
  • Product descriptionBMS-599626,98%(HPLC) 98%(HPLC)
  • Packaging10MG
  • Price$210.56
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number37687
  • Product descriptionBMS-599626,98%(HPLC) 98%(HPLC)
  • Packaging50MG
  • Price$799.68
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000992
  • Product descriptionBMS-599626 98+%
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC3105
  • Product descriptionBMS-599626(AC480) >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1142-M001 BMS-599626 ≥95% 1mg $113 2021-12-16 Buy
Adipogen Life Sciences SYN-1142-M100 BMS-599626 ≥95% 100mg $1291 2021-12-16 Buy
AK Scientific SYN1142 BMS-599626 5mg $185 2021-12-16 Buy
American Custom Chemicals Corporation HCH0045911 (S)-MORPHOLIN-3-YLMETHYL 4-(1- (3-FLUOROBENZYL)-1H-INDAZOL-5-YLAMINO) -5-METHYLPYRROLO[1,2-F][1,2,4] TRIAZIN-6-YLCARBAMATE 95.00% 5MG $499.6 2021-12-16 Buy
ApexBio Technology A2822 AC480(BMS-599626) 5mg $100 2021-12-16 Buy
ApexBio Technology A2822 AC480(BMS-599626) 10mM(in 1mL DMSO) $273 2021-12-16 Buy
ApexBio Technology A2822 AC480(BMS-599626) 25mg $300 2021-12-16 Buy
ApexBio Technology A2822 AC480(BMS-599626) 100mg $840 2021-12-16 Buy
Cayman Chemical 29657 AC480 1mg $36 2024-03-01 Buy
Cayman Chemical 29657 AC480 5mg $120 2024-03-01 Buy
Cayman Chemical 29657 AC480 10mg $223 2024-03-01 Buy
Cayman Chemical 29657 AC480 25mg $510 2024-03-01 Buy
Chem-Impex 37687 BMS-599626,98%(HPLC) 98%(HPLC) 10MG $210.56 2021-12-16 Buy
Chem-Impex 37687 BMS-599626,98%(HPLC) 98%(HPLC) 50MG $799.68 2021-12-16 Buy
Crysdot CD31000992 BMS-599626 98+% 10mg $250 2021-12-16 Buy
DC Chemicals DC3105 BMS-599626(AC480) >98% 100mg $500 2021-12-16 Buy

Properties

Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥28.35 mg/mL in DMSO
form :powder to crystal
pka :7.27±0.46(Predicted)
color :White to Light yellow to Light orange
CAS DataBase Reference :714971-09-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

It is a highly selective and potent inhibitor of HER1 and HER2 kinases and inhibits tumor cell proliferation through modulation of receptor signaling. BMS-599626 inhibits HER1/HER2 receptor heterodimerization and provides an additional mechanism of inhibiting tumors in which receptor coexpression and heterodimerization play a major role in driving tumor growth.

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