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ChemicalBook >> CAS DataBase List >> 1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine

1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine

1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine price.
  • $44 - $2691.1
  • Product name: 1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine
  • CAS: 343787-29-1
  • MF: C24H27N5O2
  • MW: 417.5
  • EINECS:
  • MDL Number:MFCD11100329
  • Synonyms:1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine;CP 673451;1-[2-[5-(2-Methoxyethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-ylamine;4-PiperidinaMine,1-[2-[5-(2-Methoxyethoxy)-1H-benziMidazol-1-yl]-8-quinolinyl]-;1-(2-(5-(2-methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine;1-[2-[5-(2-Methoxyethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-ylamine CP 673451;1-{2-[5-(2-Methoxy-ethoxy)-benzoimidazol-1-yl]-quinolin-8-yl}-piperidin-4-ylamine CP 673451;CP-673451;CP 673451;CP673451
32 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 2mg
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 200mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2336AH
  • Product description1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine
  • Packaging2mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2336AH
  • Product description1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine
  • Packaging5mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2336AH
  • Product description1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine
  • Packaging10mg
  • Price$352
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2336AH
  • Product description1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine
  • Packaging50mg
  • Price$968
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000085
  • Product descriptionCP-673451 95.00%
  • Packaging5MG
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000085
  • Product descriptionCP-673451 95.00%
  • Packaging10MG
  • Price$1039.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2173
  • Product descriptionCP-673451
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2173
  • Product descriptionCP-673451
  • Packaging10mM(in 1mL DMSO)
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2173
  • Product descriptionCP-673451
  • Packaging10mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2173
  • Product descriptionCP-673451
  • Packaging50mg
  • Price$679
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2173
  • Product descriptionCP-673451
  • Packaging200mg
  • Price$2090
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611999
  • Product descriptionCP-673451 >98%
  • Packaging100mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611999
  • Product descriptionCP-673451 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611999
  • Product descriptionCP-673451 >98%
  • Packaging1g
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19170
  • Product descriptionCP 673,451 ≥98%
  • Packaging10mg
  • Price$278
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19170
  • Product descriptionCP 673,451 ≥98%
  • Packaging5mg
  • Price$183
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2336AH 1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine 2mg $149 2021-12-16 Buy
AK Scientific 2336AH 1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine 5mg $228 2021-12-16 Buy
AK Scientific 2336AH 1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine 10mg $352 2021-12-16 Buy
AK Scientific 2336AH 1-(2-(5-(2-Methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine 50mg $968 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000085 CP-673451 95.00% 5MG $640 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000085 CP-673451 95.00% 10MG $1039.5 2021-12-16 Buy
ApexBio Technology B2173 CP-673451 5mg $119 2021-12-16 Buy
ApexBio Technology B2173 CP-673451 10mM(in 1mL DMSO) $160 2021-12-16 Buy
ApexBio Technology B2173 CP-673451 10mg $225 2021-12-16 Buy
ApexBio Technology B2173 CP-673451 50mg $679 2021-12-16 Buy
ApexBio Technology B2173 CP-673451 200mg $2090 2021-12-16 Buy
Biorbyt Ltd orb611999 CP-673451 >98% 100mg $765 2021-12-16 Buy
Biorbyt Ltd orb611999 CP-673451 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb611999 CP-673451 >98% 1g $2691.1 2021-12-16 Buy
Cayman Chemical 19170 CP 673,451 ≥98% 10mg $278 2024-03-01 Buy
Cayman Chemical 19170 CP 673,451 ≥98% 5mg $183 2024-03-01 Buy

Properties

Boiling point :656.3±65.0 °C(Predicted)
Density :1.32
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥2.39 mg/mL in EtOH with gentle warming and ultrasonic; ≥20.9 mg/mL in DMSO
form :Powder
pka :9.84±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CP-673,451 is a selective inhibitor of the platelet-derived growth factor receptor β (PDGFRβ) kinase with an IC50 value of 1 nM. It also inhibits the PDGFRα kinase (IC50 = 10 nM), but exhibits greater than 450-fold selectivity over other angiogenic receptors such as VEGFR 2, TIE-2, and FGR2. In several in vivo tumor models, CP-673,451 has antiangiogenic and antitumor activity.

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