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ChemicalBook >> CAS DataBase List >> N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide

N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide price.
  • $50 - $3587
  • Product name: N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide
  • CAS: 312917-14-9
  • MF: C20H16N2OS
  • MW: 332.42
  • EINECS:
  • MDL Number:MFCD01005305
  • Synonyms:N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide;TCS JNK 5a;1-NaphthalenecarboxaMide, N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-;SC-202671;N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide;N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide JNK Inhibitor IX;N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide;N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)naphthalene-1-carboxamide
26 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 10
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2492AH
  • Product descriptionNaphthalene-1-carboxylicacid(3-cyano-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl)-amide
  • Packaging1g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA222483
  • Product descriptionJNKInhibitorIX 98+%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA222483
  • Product descriptionJNKInhibitorIX 98+%
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA222483
  • Product descriptionJNKInhibitorIX 98+%
  • Packaging50mg
  • Price$214
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA222483
  • Product descriptionJNKInhibitorIX 98+%
  • Packaging1g
  • Price$3587
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001372
  • Product descriptionJNK INHIBITOR IX 95.00%
  • Packaging5MG
  • Price$173.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3275
  • Product descriptionTCSJNK5a
  • Packaging25mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS483160
  • Product descriptionJNKInhibitorIX ≥98%
  • Packaging50mg
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15624
  • Product descriptionJNK Inhibitor IX ≥98%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15624
  • Product descriptionJNK Inhibitor IX ≥98%
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15624
  • Product descriptionJNK Inhibitor IX ≥98%
  • Packaging25mg
  • Price$225
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15624
  • Product descriptionJNK Inhibitor IX ≥98%
  • Packaging50mg
  • Price$419
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM252122
  • Product descriptionTCSJNK5a 98%
  • Packaging50mg
  • Price$269
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2690
  • Product descriptionTCSJNK5a 98.06%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2690
  • Product descriptionTCSJNK5a 98.06%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2690
  • Product descriptionTCSJNK5a 98.06%
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2492AH Naphthalene-1-carboxylicacid(3-cyano-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl)-amide 1g $180 2021-12-16 Buy
Ambeed A222483 JNKInhibitorIX 98+% 5mg $50 2021-12-16 Buy
Ambeed A222483 JNKInhibitorIX 98+% 10mg $84 2021-12-16 Buy
Ambeed A222483 JNKInhibitorIX 98+% 50mg $214 2021-12-16 Buy
Ambeed A222483 JNKInhibitorIX 98+% 1g $3587 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001372 JNK INHIBITOR IX 95.00% 5MG $173.8 2021-12-16 Buy
ApexBio Technology B3275 TCSJNK5a 25mg $136 2021-12-16 Buy
Arctom AS483160 JNKInhibitorIX ≥98% 50mg $212 2021-12-16 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 5mg $62 2024-03-01 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 10mg $109 2024-03-01 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 25mg $225 2024-03-01 Buy
Cayman Chemical 15624 JNK Inhibitor IX ≥98% 50mg $419 2024-03-01 Buy
Chemenu CM252122 TCSJNK5a 98% 50mg $269 2021-12-16 Buy
ChemScene CS-2690 TCSJNK5a 98.06% 5mg $50 2021-12-16 Buy
ChemScene CS-2690 TCSJNK5a 98.06% 10mg $90 2021-12-16 Buy
ChemScene CS-2690 TCSJNK5a 98.06% 50mg $250 2021-12-16 Buy

Properties

Melting point :88-90oC
Boiling point :486.8±45.0 °C(Predicted)
Density :1.32±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 13 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming)
form :Tan solid
pka :11.95±0.20(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

c-Jun N-terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. They have been implicated in neurodegeneration, rheumatoid arthritis, inflammation, cancer, and diabetes. JNK1 and JNK2 are widely expressed throughout the body whereas JNK3 is predominantly distributed in the brain. JNK Inhibitor IX is a thienylnaphthamide compound that targets the ATP binding site of JNK2 and JNK3, disrupting activity with pIC50 values of 6.5 and 6.7, respectively. It demonstrates little activity against JNK1, p38α, and a panel of more than 30 other kinases (pIC50 < 5.0).

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