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ChemicalBook >> CAS DataBase List >> N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide price.
  • $7 - $1815
  • Product name: N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide
  • CAS: 302964-08-5
  • MF: C16H13Cl2N5OS
  • MW: 394.28
  • EINECS:695-686-7
  • MDL Number:MFCD11045075
  • Synonyms:2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide;5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-;Dasatinib Intermediate 1;2-(6-Chloro-2-MethylpyriMidin-4-ylaMino)-N-(2-chloro-6-Methyl;2-[(6-chloro-2-MethylpyriMidin-4-yl)aMino]-N-(2-chloro-6-Methylphenyl)-1,3-thiazole-5-carboxaMide;N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-yrimidinyl)amino]-5-thiazolecarboxamide;N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino];CAY10697
31 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemcia Scientific
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
Package
  • 50mg
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  • 1g
  • 2g
  • 2.5G
  • 5g
  • 10g
  • 25g
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  • ManufacturerAK Scientific
  • Product numberJ95020
  • Product description2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
  • Packaging10g
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ95020
  • Product description2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
  • Packaging25g
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA160437
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA160437
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging1g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA160437
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging5g
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA160437
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging10g
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA160437
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging25g
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA160437
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging100g
  • Price$412
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0014257
  • Product descriptionN-(2-CHLORO-6-METHYLPHENYL)-2-[(6-CHLORO-2-METHYL-4-PYRIMIDINYL)AMINO]-5-THIAZOLECARBOXAMIDE 95.00%
  • Packaging250MG
  • Price$721.88
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0014257
  • Product descriptionN-(2-CHLORO-6-METHYLPHENYL)-2-[(6-CHLORO-2-METHYL-4-PYRIMIDINYL)AMINO]-5-THIAZOLECARBOXAMIDE 95.00%
  • Packaging2.5G
  • Price$1815
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR302262
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging5g
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR302262
  • Product description2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95%
  • Packaging25g
  • Price$508
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC33881
  • Product description2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
  • Packaging2g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC33881
  • Product description2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
  • Packaging5G
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC33881
  • Product description2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
  • Packaging10g
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC33881
  • Product description2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
  • Packaging25g
  • Price$250
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J95020 2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 10g $115 2021-12-16 Buy
AK Scientific J95020 2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 25g $225 2021-12-16 Buy
Ambeed A160437 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 250mg $7 2021-12-16 Buy
Ambeed A160437 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 1g $10 2021-12-16 Buy
Ambeed A160437 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 5g $30 2021-12-16 Buy
Ambeed A160437 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 10g $54 2021-12-16 Buy
Ambeed A160437 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 25g $120 2021-12-16 Buy
Ambeed A160437 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 100g $412 2021-12-16 Buy
American Custom Chemicals Corporation HCH0014257 N-(2-CHLORO-6-METHYLPHENYL)-2-[(6-CHLORO-2-METHYL-4-PYRIMIDINYL)AMINO]-5-THIAZOLECARBOXAMIDE 95.00% 250MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation HCH0014257 N-(2-CHLORO-6-METHYLPHENYL)-2-[(6-CHLORO-2-METHYL-4-PYRIMIDINYL)AMINO]-5-THIAZOLECARBOXAMIDE 95.00% 2.5G $1815 2021-12-16 Buy
Apolloscientific OR302262 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 5g $182 2021-12-16 Buy
Apolloscientific OR302262 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 95% 25g $508 2021-12-16 Buy
Biosynth Carbosynth FC33881 2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 2g $65 2021-12-16 Buy
Biosynth Carbosynth FC33881 2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 5G $100 2021-12-16 Buy
Biosynth Carbosynth FC33881 2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 10g $160 2021-12-16 Buy
Biosynth Carbosynth FC33881 2-(6-Chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 25g $250 2021-12-16 Buy

Properties

Melting point :333-335°C
Boiling point :566.95° C (Predicted)
Density :1.516±0.06 g/cm3(Predicted)
refractive index :n20D 1.72 (Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO (Slightly)
pka :10.92±0.70(Predicted)
form :Solid
color :Pale Yellow
Water Solubility :Slightly soluble in water
InChI :InChI=1S/C16H13Cl2N5OS/c1-8-4-3-5-10(17)14(8)23-15(24)11-7-19-16(25-11)22-13-6-12(18)20-9(2)21-13/h3-7H,1-2H3,(H,23,24)(H,19,20,21,22)
InChIKey :LMXUWARKUIELGT-UHFFFAOYSA-N
SMILES :S1C(C(NC2=C(C)C=CC=C2Cl)=O)=CN=C1NC1C=C(Cl)N=C(C)N=1
CAS DataBase Reference :302964-08-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dasatinib is a potent inhibitor of receptor and non-receptor tyrosine kinases, including some drug resistant mutant forms. It has potential therapeutic value in diseases that are characterized by elevated levels of these kinases, including some forms of cancer and fibrotic disease. CAY10697 is an intermediate in the synthesis of dasatinib.

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