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ChemicalBook >> CAS DataBase List >> 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE

1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE price.
  • $32 - $1105.76
  • Product name: 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE
  • CAS: 284028-90-6
  • MF: C8H10N2OS
  • MW: 182.24
  • EINECS:200-589-5
  • MDL Number:MFCD08703132
  • Synonyms:1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE;DR 2313;7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one;3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one;4H-Thiopyrano[4,3-d]pyriMidin-4-one,3,5,7,8-tetrahydro-2;4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE,3,5,7,8-TETRAHYDRO-2-METHYL-;SC-202756;2-Methyl-1-sulfanyl-1H,4H,5H,7H,8H-pyrano[4,3-d]pyriMidin-4-one
19 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1
  • 1mg
  • 50
  • 5mg
  • 10MG
  • 25mg
  • 50MG
  • ManufacturerAK Scientific
  • Product number2779AB
  • Product description7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one
  • Packaging5mg
  • Price$181
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000123
  • Product description1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE 95.00%
  • Packaging10MG
  • Price$685.57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000123
  • Product description1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE 95.00%
  • Packaging50MG
  • Price$1105.76
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4527
  • Product descriptionDR2313
  • Packaging1mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4527
  • Product descriptionDR2313
  • Packaging10mg
  • Price$251
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4527
  • Product descriptionDR2313
  • Packaging50mg
  • Price$1032
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1268
  • Product descriptionDR2313 99%
  • Packaging50mg
  • Price$396
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21181
  • Product descriptionDR2313 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21181
  • Product descriptionDR2313 ≥98%
  • Packaging5mg
  • Price$74
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21181
  • Product descriptionDR2313 ≥98%
  • Packaging10mg
  • Price$122
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21181
  • Product descriptionDR2313 ≥98%
  • Packaging25mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0397
  • Product descriptionDR2313 ≥98% (HPLC)
  • Packaging25mg
  • Price$337
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0397
  • Product descriptionDR2313 ≥98% (HPLC)
  • Packaging5mg
  • Price$78.3
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2496
  • Product descriptionDR2313 ≥99%(HPLC)
  • Packaging1
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2496
  • Product descriptionDR2313 ≥99%(HPLC)
  • Packaging10
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2496
  • Product descriptionDR2313 ≥99%(HPLC)
  • Packaging50
  • Price$472
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2779AB 7,8-Dihydro-2-methyl-1H-thiopyrano[4,3-d]pyrimidin-4(5H)-one 5mg $181 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000123 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE 95.00% 10MG $685.57 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000123 1,5,7,8-TETRAHYDRO-2-METHYL-4H-THIOPYRANO[4,3-D]PYRIMIDIN-4-ONE 95.00% 50MG $1105.76 2021-12-16 Buy
ApexBio Technology A4527 DR2313 1mg $119 2021-12-16 Buy
ApexBio Technology A4527 DR2313 10mg $251 2021-12-16 Buy
ApexBio Technology A4527 DR2313 50mg $1032 2021-12-16 Buy
Axon Medchem Axon1268 DR2313 99% 50mg $396 2021-12-16 Buy
Cayman Chemical 21181 DR2313 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 21181 DR2313 ≥98% 5mg $74 2024-03-01 Buy
Cayman Chemical 21181 DR2313 ≥98% 10mg $122 2024-03-01 Buy
Cayman Chemical 21181 DR2313 ≥98% 25mg $230 2024-03-01 Buy
Sigma-Aldrich SML0397 DR2313 ≥98% (HPLC) 25mg $337 2022-05-15 Buy
Sigma-Aldrich SML0397 DR2313 ≥98% (HPLC) 5mg $78.3 2024-03-01 Buy
Tocris 2496 DR2313 ≥99%(HPLC) 1 $60 2021-12-16 Buy
Tocris 2496 DR2313 ≥99%(HPLC) 10 $116 2021-12-16 Buy
Tocris 2496 DR2313 ≥99%(HPLC) 50 $472 2021-12-16 Buy

Properties

Boiling point :349.3±52.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :H2O: >2mg/mL (warmed)
pka :1.54±0.20(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PARP Inhibitor XI, DR2313 is a water soluble pyrimidinone compound that functions as a PARP (Poly(ADP-ribose) polymerase) inhibitor. PARP (Poly(ADP-ribose) polymerase) function by triggering DNA repair mechanisms and activating apoptosis in damaged cells. Studies show that DR2313 competes with NAD+ but does not display selectivity among PARP-1 and PARP-2. In addition, in vitro studies of cerebral ischemia exhibiting an overactivation of PARP show that ischemic damage can be reduced by introducing DR2313.

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