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ChemicalBook >> CAS DataBase List >> DPQ

DPQ

DPQ price.
  • $45 - $730
  • Product name: DPQ
  • CAS: 129075-73-6
  • MF: C18H26N2O2
  • MW: 302.41
  • EINECS:
  • MDL Number:MFCD02258932
  • Synonyms:PARP Inhibitor III, DPQ ;DPQ;3,4-DIHYDRO-5-[4-(1-PIPERIDINYL)BUTOXY]-1(2H)-ISOQUINOLINONE;3,4-DIHYDRO-5[4-(1-PIPERIDINYL)BUTOXYL]-1(2H)-ISOQUINOLINE;3,4-DIHYDRO-5-[4-(1-PIPERIDINYL)BUTOXYL]-1(2H)-ISOQUINOLINONE;3,4-DIHYDRO-5[4-(1-PIPERINDINYL)BUTOXY]-1(2H)-ISOQUINOLINE;5-[4-(1-PIPERIDINYL)-BUTYLOXY]-1,2,3,4-TETRAHYDROISOQUINOLIN-1-ONE;DMEM(Low Glucose)
10 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 25mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0037-M005
  • Product descriptionDPQ ≥99%(NMR)
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4445CR
  • Product description3,4-Dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone
  • Packaging5mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14450
  • Product descriptionDPQ ≥99%
  • Packaging1mg
  • Price$56
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14450
  • Product descriptionDPQ ≥99%
  • Packaging5mg
  • Price$201
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD5314
  • Product descriptionDPQ ≥98% (HPLC), solid
  • Packaging5mg
  • Price$443
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD5314
  • Product descriptionDPQ ≥98% (HPLC), solid
  • Packaging1mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number300270
  • Product descriptionPARP Inhibitor III, DPQ
  • Packaging1mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD446430
  • Product description3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD446430
  • Product description3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone
  • Packaging25mg
  • Price$730
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number044763
  • Product descriptionDPQ
  • Packaging1mg
  • Price$282
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0037-M005 DPQ ≥99%(NMR) 5mg $160 2021-12-16 Buy
AK Scientific 4445CR 3,4-Dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone 5mg $322 2021-12-16 Buy
Cayman Chemical 14450 DPQ ≥99% 1mg $56 2024-03-01 Buy
Cayman Chemical 14450 DPQ ≥99% 5mg $201 2024-03-01 Buy
Sigma-Aldrich D5314 DPQ ≥98% (HPLC), solid 5mg $443 2024-03-01 Buy
Sigma-Aldrich D5314 DPQ ≥98% (HPLC), solid 1mg $130 2024-03-01 Buy
Sigma-Aldrich 300270 PARP Inhibitor III, DPQ 1mg $130 2024-03-01 Buy
TRC D446430 3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone 1mg $45 2021-12-16 Buy
TRC D446430 3,4-Dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-isoquinolinone 25mg $730 2021-12-16 Buy
Usbiological 044763 DPQ 1mg $282 2021-12-16 Buy

Properties

Melting point :107-109°
Boiling point :528.8±50.0 °C(Predicted)
Density :1.096±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: Soluble
form :solid
pka :14.54±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. DPQ is a potent inhibitor of PARPs, inhibiting PARP1 with an IC50 value of 40 nM. It is approximately 10-fold less potent against PARP2. DPQ can be used in either cells or in animals.

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