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ChemicalBook >> CAS DataBase List >> 2-AG

2-AG

2-AG price.
  • $37 - $503.92
  • Product name: 2-AG
  • CAS: 53847-30-6
  • MF: C23H38O4
  • MW: 378.55
  • EINECS:200-835-2
  • MDL Number:MFCD01862600
  • Synonyms:5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 2-GLYCERYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENOIC ACID, 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL ESTER;2-AG;NOLADIN;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoicacid;2-Hydroxy-1-(hydroxymethyl)ethylester;1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate;2-Ara-gl
7 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
  • Tocris
Package
  • 10
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0004988
  • Product description2-ARACHIDONYL GLYCEROL 95.00%
  • Packaging5MG
  • Price$503.92
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number62160
  • Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number62160
  • Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
  • Packaging5mg
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number62160
  • Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
  • Packaging10mg
  • Price$198
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number62160
  • Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
  • Packaging25mg
  • Price$360
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA8973
  • Product description2-Arachidonyl glycerol ~10 mg/mL, ≥98% (HPLC)
  • Packaging5mg
  • Price$398
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number1298
  • Product description2-Arachidonyl glycerol
  • Packaging10
  • Price$207
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation LIP0004988 2-ARACHIDONYL GLYCEROL 95.00% 5MG $503.92 2021-12-16 Buy
Cayman Chemical 62160 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) 1mg $37 2024-03-01 Buy
Cayman Chemical 62160 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) 5mg $135 2024-03-01 Buy
Cayman Chemical 62160 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) 10mg $198 2024-03-01 Buy
Cayman Chemical 62160 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) 25mg $360 2024-03-01 Buy
Sigma-Aldrich A8973 2-Arachidonyl glycerol ~10 mg/mL, ≥98% (HPLC) 5mg $398 2024-03-01 Buy
Tocris 1298 2-Arachidonyl glycerol 10 $207 2021-12-16 Buy

Properties

Boiling point :508.6±50.0 °C(Predicted)
Density :0.992±0.06 g/cm3(Predicted)
Flash point :2 °C
storage temp. :-20°C
solubility :DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml
form :acetonitrile solution
pka :13.54±0.10(Predicted)
color :Colorless to light yellow
CAS DataBase Reference :53847-30-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 and CB2 receptors (Kis = 58 and 145 nM, respectively). Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system; it is the most abundant molecular species of monoacylglycerol found in rat brain. Formation of 2-AG is calcium-dependent and is mediated by the activities of PLC and DAG lipase. 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a CB1 receptor-dependent mechanism. 2-AG is metabolized in vitro by MAG lipase and fatty acid amide hydrolase, with MAG lipase likely being the principle metabolizing enzyme in vivo.

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