2-AG
- $37 - $503.92
- Product name: 2-AG
- CAS: 53847-30-6
- MF: C23H38O4
- MW: 378.55
- EINECS:200-835-2
- MDL Number:MFCD01862600
- Synonyms:5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 2-GLYCERYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENOIC ACID, 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL ESTER;2-AG;NOLADIN;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoicacid;2-Hydroxy-1-(hydroxymethyl)ethylester;1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate;2-Ara-gl
7 prices
Selected condition:
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- Sigma-Aldrich
- Tocris
Package
- 10
- 1mg
- 5MG
- 10mg
- 25mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0004988
- Product description2-ARACHIDONYL GLYCEROL 95.00%
- Packaging5MG
- Price$503.92
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number62160
- Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number62160
- Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
- Packaging5mg
- Price$135
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number62160
- Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
- Packaging10mg
- Price$198
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number62160
- Product description2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG)
- Packaging25mg
- Price$360
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberA8973
- Product description2-Arachidonyl glycerol ~10 mg/mL, ≥98% (HPLC)
- Packaging5mg
- Price$398
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1298
- Product description2-Arachidonyl glycerol
- Packaging10
- Price$207
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
American Custom Chemicals Corporation | LIP0004988 | 2-ARACHIDONYL GLYCEROL 95.00% | 5MG | $503.92 | 2021-12-16 | Buy |
Cayman Chemical | 62160 | 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) | 1mg | $37 | 2024-03-01 | Buy |
Cayman Chemical | 62160 | 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) | 5mg | $135 | 2024-03-01 | Buy |
Cayman Chemical | 62160 | 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) | 10mg | $198 | 2024-03-01 | Buy |
Cayman Chemical | 62160 | 2-Arachidonoyl Glycerol ≥95% (as a 9:1 mixture of the 2-AG and 1-AG) | 25mg | $360 | 2024-03-01 | Buy |
Sigma-Aldrich | A8973 | 2-Arachidonyl glycerol ~10 mg/mL, ≥98% (HPLC) | 5mg | $398 | 2024-03-01 | Buy |
Tocris | 1298 | 2-Arachidonyl glycerol | 10 | $207 | 2021-12-16 | Buy |
Properties
Boiling point :508.6±50.0 °C(Predicted)
Density :0.992±0.06 g/cm3(Predicted)
Flash point :2 °C
storage temp. :-20°C
solubility :DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml
form :acetonitrile solution
pka :13.54±0.10(Predicted)
color :Colorless to light yellow
CAS DataBase Reference :53847-30-6(CAS DataBase Reference)
Density :0.992±0.06 g/cm3(Predicted)
Flash point :2 °C
storage temp. :-20°C
solubility :DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml
form :acetonitrile solution
pka :13.54±0.10(Predicted)
color :Colorless to light yellow
CAS DataBase Reference :53847-30-6(CAS DataBase Reference)
Safety Information
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Description
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 and CB2 receptors (Kis = 58 and 145 nM, respectively). Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system; it is the most abundant molecular species of monoacylglycerol found in rat brain. Formation of 2-AG is calcium-dependent and is mediated by the activities of PLC and DAG lipase. 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a CB1 receptor-dependent mechanism. 2-AG is metabolized in vitro by MAG lipase and fatty acid amide hydrolase, with MAG lipase likely being the principle metabolizing enzyme in vivo.Related product price
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