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ChemicalBook >> CAS DataBase List >> IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea

IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea

IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea price.
  • $27 - $2395.3
  • Product name: IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea
  • CAS: 196868-63-0
  • MF: C18H16ClN3O2
  • MW: 341.79
  • EINECS:
  • MDL Number:MFCD00160558
  • Synonyms:IGF-1R Inhibitor II, N-(5-Chloro-2-methoxyphenyl)-Nμ-(2-methylquinolin-4-yl)urea;PQ401;N-(5-Chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)urea;IGF-1R Inhibitor II;N-(5-Chloro-2-methoxyphenyl)-N′-(2-methylquinolin-4-yl)urea;Urea, N-(5-chloro-2-Methoxyphenyl)-N'-(2-Methyl-4-quinolinyl)-;1-(5-Chloro-2-Methoxyphenyl)-3-(2-Methylquinolin-4-yl)urea;N-(5-chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)-
46 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number0143AB
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
  • Packaging5mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0143AB
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
  • Packaging10mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165138
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+%
  • Packaging1mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165138
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+%
  • Packaging5mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165138
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+%
  • Packaging10mg
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165138
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+%
  • Packaging50mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165138
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+%
  • Packaging100mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165138
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+%
  • Packaging250mg
  • Price$359
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165138
  • Product description1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+%
  • Packaging1g
  • Price$863
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003904
  • Product descriptionPQ401 95.00%
  • Packaging10MG
  • Price$286.65
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003904
  • Product descriptionPQ401 95.00%
  • Packaging50MG
  • Price$1138.78
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2033
  • Product descriptionPQ401
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2033
  • Product descriptionPQ401
  • Packaging10mM(in 1mL DMSO)
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2033
  • Product descriptionPQ401
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2033
  • Product descriptionPQ401
  • Packaging100mg
  • Price$554
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS460241
  • Product descriptionPQ401 ≥98%
  • Packaging1mg
  • Price$27
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0143AB 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 5mg $185 2021-12-16 Buy
AK Scientific 0143AB 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 10mg $235 2021-12-16 Buy
Ambeed A165138 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+% 1mg $27 2021-12-16 Buy
Ambeed A165138 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+% 5mg $53 2021-12-16 Buy
Ambeed A165138 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+% 10mg $91 2021-12-16 Buy
Ambeed A165138 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+% 50mg $130 2021-12-16 Buy
Ambeed A165138 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+% 100mg $232 2021-12-16 Buy
Ambeed A165138 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+% 250mg $359 2021-12-16 Buy
Ambeed A165138 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea 98+% 1g $863 2021-12-16 Buy
American Custom Chemicals Corporation API0003904 PQ401 95.00% 10MG $286.65 2021-12-16 Buy
American Custom Chemicals Corporation API0003904 PQ401 95.00% 50MG $1138.78 2021-12-16 Buy
ApexBio Technology A2033 PQ401 5mg $68 2021-12-16 Buy
ApexBio Technology A2033 PQ401 10mM(in 1mL DMSO) $106 2021-12-16 Buy
ApexBio Technology A2033 PQ401 25mg $200 2021-12-16 Buy
ApexBio Technology A2033 PQ401 100mg $554 2021-12-16 Buy
Arctom AS460241 PQ401 ≥98% 1mg $27 2021-12-16 Buy

Properties

Density :1.370±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >10mg/mL
form :White solid
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PQ401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation. The mechanism of inhibition likely involves indirect blocking of ATP binding. PQ401 also decreases IGF-1R-dependent tumor cell growth in vitro.