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ChemicalBook >> CAS DataBase List >> 12(S)-HEPE

12(S)-HEPE

12(S)-HEPE price.
  • $153 - $547
  • Product name: 12(S)-HEPE
  • CAS: 116180-17-7
  • MF: C20H30O3
  • MW: 318.45
  • EINECS:
  • MDL Number:MFCD00132915
  • Synonyms:12(S)-HEPE;12S-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID;MCRJLMXYVFDXLS-UOLHMMFFSA-N;5,8,10,14,17-Eicosapentaenoic acid, 12-hydroxy-, (5Z,8Z,10E,12S,14Z,17Z)-;12(S)HEPE,12(S) HEPE
4 prices
Selected condition：
Brand
  • Cayman Chemical
  • TRC
Package
  • 25μg
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number32550
  • Product description12(S)-HEPE ≥98%
  • Packaging25μg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number32550
  • Product description12(S)-HEPE ≥98%
  • Packaging50μg
  • Price$290
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number32550
  • Product description12(S)-HEPE ≥98%
  • Packaging100μg
  • Price$547
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberH290013
  • Product description12(S)-HEPE
  • Packaging50μg
  • Price$280
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 32550 12(S)-HEPE ≥98% 25μg $153 2024-03-01 Buy
Cayman Chemical 32550 12(S)-HEPE ≥98% 50μg $290 2024-03-01 Buy
Cayman Chemical 32550 12(S)-HEPE ≥98% 100μg $547 2024-03-01 Buy
TRC H290013 12(S)-HEPE 50μg $280 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.

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