PENTACHLOROBENZENE
Product identifier
- Product name: PENTACHLOROBENZENE
- CBnumber: CB6120698
- CAS: 608-93-5
- EINECS Number: 210-172-0
- Synonyms: pentachlorobenzene,Benzene, pentachloro-
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Flammable solids, Category 1
Acute toxicity - Category 4, Oral
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Label elements
Pictogram(s)
- Signal wordDanger
H228 Flammable solid
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
H351 Suspected of causing cancer
H373 May cause damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P281 Use personal protective equipment as required.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501 Dispose of contents/container to..…
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P370+P378 In case of fire: Use ... to extinguish.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: PENTACHLOROBENZENE
- Synonyms: pentachlorobenzene,Benzene, pentachloro-
- CAS: 608-93-5
- EC number: 210-172-0
- MF: C6HCl5
- MW: 250.34
Description of first aid measures
If inhaledFresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Most important symptoms and effects, both acute and delayed
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)
Indication of any immediate medical attention and special treatment needed
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aromatic hydrocarbons and related compounds
Extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special protective equipment for fire-fighters: Wear self contained breathing apparatus for fire fighting if necessary.
Specific Hazards Arising from the Chemical
Flash point data for this compound are not available but it is probably non-flammable. (NTP, 1992)
Advice for firefighters
Use water spray, powder, foam, carbon dioxide.
Personal precautions, protective equipment and emergency procedures
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Personal precautions: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Sweep up and shovel. Contain spillage, and then collect with an electrically protected vacuum cleaner or by wetbrushing and place in container for disposal according to local regulations. Keep in suitable, closed containers for disposal. Contain spillage, pick up with an electrically protected vacuum cleaner or by wet-brushing and transfer to a container for disposal according to local regulations.
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing.Keep container tightly closed in a dry and well-ventilated place.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety spectacles.
Protective gloves.
Use local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateneat
- ColourWhite needles
- Odour
Pleasant aroma
- Melting point/freezing point
84-87°C
- Boiling point or initial boiling point and boiling range
275°C
- Flammability
Combustible under specific conditions. Gives off irritating or toxic fumes (or gases) in a fire.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
131.6°C
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- SolubilityVery soluble in ether (Sax and Lewis, 1987)
- Partition coefficient n-octanol/water
log Kow = 5.18
- Vapour pressure6 x 10-3 mmHg at 20–30 °C (quoted, Mercer et al., 1990)
- Density and/or relative density
1.609 g/mL at 25°C(lit.)
- Relative vapour density
(air = 1): 8.6
- Particle characteristics
no data available
Reactivity
Decomposes on burning. This produces toxic and corrosive fumes including hydrogen chloride.
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
Not flammable or combustible.PENTACHLOROBENZENE is relatively unreactive. May be incompatible with strong oxidizing and reducing agents. Also may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Conditions to avoid
no data available
Incompatible materials
On contact with acids or acid fumes ... /chlorides/ evolve highly toxic /hydrogen chloride/ fumes. Chlorides
Hazardous decomposition products
When heated to decomp it emits ... fumes of /hydrogen chloride/.
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
CLASSIFICATION: D; not classifiable as to human carcinogenicity. BASIS FOR CLASSIFICATION: No human data and no animal data available. HUMAN CARCINOGENICITY DATA: None. ANIMAL CARCINOGENICITY DATA: None.
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
The substance may have effects on the liver. This may result in liver impairment. Animal tests show that this substance possibly causes toxicity to human reproduction or development.
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
Toxicity
- Toxicity to fish: LC50; Species: /Lepomis macrochirus/ (Bluegill sunfish); Concentration: 2.27 mg/L for 24 hr; 0.55 mg/L for 48 hr; 0.25 mg/L for 96 hr /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green Algae); Conditions: freshwater, static; Concentration: 32000 ug/L for 24 hr; Effect: population, chlorophyll A concentration /formulation
- Toxicity to microorganisms: no data available
Persistence and degradability
Chlorinated benzenes (including pentachlorobenzene) were stable under both aerobic and anaerobic conditions. (36)C-labeled chlorinated hydrocarbons were prepared and incubated with mixed microbial cultures obtained aerobically or anaerobically from arable soil or sewage sludge. Pentachlorobenzene showed slight dechlorination (3-4%) during anaerobic incubation with Clostridia and with aerobic Pseudomonas species.
Bioaccumulative potential
BCF values of 1,400 to 6,800 were measured in carp exposed to 10 ug/L of pentachlorobenzene during an 8 week incubation period and BCF values of 1,100 to 5,100 were measured in carp exposed to 1 ug/L of pentachlorobenzene during an 8 week incubation period(1). BCF values in trout were reported as 13,000-20,000(2). An experimental pentachlorobenzene BCF of approximately 5,000 was reported (fish species not reported)(3). An experimental BCF of 4790 was reported for guppy(4). In 56-day exposure studies using carp, pentachlorobenzene BCFs ranged from 4967 to 5656 in the presence or absence of various dispersants(5). In 10-day exposure studies using fathead minnow (Pimephales promelas), pentachlorobenzene BCFs ranged from 1085 to 1773(6). According to a classification scheme(7), these BCF values suggest that bioconcentration in aquatic organisms is very high, provided the compound is not metabolized by the organism(SRC).
Mobility in soil
Pentachlorobenzene has measured log Koc value of 3.5 (Koc of 3162) reported for soils(1). A log Koc value of 5.1 (Koc of 1.26X10+5) was reported for pentachlorobenzene in a freshwater river sediment(2). A log Koc value of 4.6 (Koc of 3.98X10+4) was reported for pentachlorobenzene in sediment obtained from the Ise Bay, Japan(3). A Koc of 4.0X10+4 was determined for adsorption on to whole bottom sediments from a stream(4). Log Koc values of 6.72 and 6.25 (Koc values of 5.24X10+6 and 1.78X10+6) were determined for two sediment layers from a lake(5). Pentachlorobenzene was found to desorb very slowly from sediment in water(6). According to a classification scheme(2), these measured Koc values suggest that pentachlorobenzene is expected to have slight to no mobility in soil.
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN1325 (For reference only, please check.)
IMDG: UN1325 (For reference only, please check.)
IATA: UN1325 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: FLAMMABLE SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IMDG: FLAMMABLE SOLID, ORGANIC, N.O.S. (For reference only, please check.)
IATA: FLAMMABLE SOLID, ORGANIC, N.O.S. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 4.1 (For reference only, please check.)
IMDG: 4.1 (For reference only, please check.)
IATA: 4.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Depending on the degree of exposure, periodic medical examination is suggested.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.