m-Cresol
Product identifier
- Product name: m-Cresol
- CBnumber: CB7852747
- CAS: 108-39-4
- EINECS Number: 203-577-9
- Synonyms: m-cresol,3-methylphenol
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: m-Cresol
- Synonyms: m-cresol,3-methylphenol
- CAS: 108-39-4
- EC number: 203-577-9
- MF: C7H8O
- MW: 108.14
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Full contact
Material: Chloroprene
Minimum layer thickness: 0,65 mm Break through time: 480 min Material tested:KCL 720 Camapren?
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Splash contact Material: Latex gloves
Minimum layer thickness: 0,6 mm Break through time: 60 min
Material tested:Lapren? (KCL 706 / Aldrich Z677558, Size M)
protective clothing
Recommended Filter type: Filter A-(P3)
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless, light yellow liquid
- Odourphenol-like
- Odour Threshold0.0001ppm
- pH5 (20g/l, H2O, 20℃)
- Melting point/freezing pointMelting point/range: 8 - 10 °C - lit.
- Initial boiling point and boiling range203 °C - lit.
- Flash point86 °C - closed cup
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 1,35 %(V) Lower explosion limit: 1,06 %(V)
- Vapour pressure< 1 hPa at 20 °C
- Vapour density 3,73 - (Air = 1.0)
- Relative density1,03 at 20 °C
- Water solubility22,7 g/l at 25 °C
- Partition coefficient: n-octanol/waterlog Pow: 1,96 - Bioaccumulation is not expected.
- Autoignition temperature559 °C at 1.013 hPa
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 6,18 mPa.s at 40 °C20,8 mPa.s at 20 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
- λmax273nm(lit.)
Other safety information
Dissociation constant 10,09 at 25 °C
Relative vapor density
3,73 - (Air = 1.0)
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
Violent reactions possible with:
Strong oxidizing agents Nitric acid
fuming sulfuric acid chlorosulfonic acid alkalines
Conditions to avoid
Strong heating.
Incompatible materials
bronze, brass, Iron, Lead
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicity(OECD Test Guideline 401)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract
LD50 Dermal - Rabbit - 620 mg/kg
Remarks: Behavioral:Somnolence (general depressed activity). Behavioral:Tetany.
(RTECS)
Result: Causes burns. - 24 h Remarks: (ECHA)
Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473
Result: positive
Test Type: In vitro mammalian cell gene mutation test Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Chromosome aberration test Species: Mouse
Cell type: Bone marrow Application Route: Oral
Method: OECD Test Guideline 475 Result: negative
Toxicity
static test LC50 - Oncorhynchus mykiss (rainbow trout) - 8,6 mg/l - 96 h
Remarks: (ECHA)
static test LC50 - Salmo trutta (brown trout) - 8,4 mg/l - 96 h Remarks: (ECHA)
flow-through test EC50 - Daphnia pulicaria - > 99,5 mg/l - 48 h (US-EPA)
Persistence and degradability
Biodegradability aerobic - Exposure time 10 d
Result: 96 % - Inherently biodegradable. (OECD Test Guideline 302B)
Bioaccumulative potential
Bioaccumulation Leuciscus idus (Golden orfe) - 3 d
- 0,05 mg/l(meta-Cresol)
Bioconcentration factor (BCF): 17 - 20
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Biological effects:
Hazard for drinking water supplies.
Change in the flavour characteristics of fish protein. Discharge into the environment must be avoided.
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
IncompatibilitiesVapors may form explosive mixture with air. Incompatible with strong acids; oxidizers, alkalies, aliphatic amines; amides, chlorosulfonic acid; oleum. Decomposes on heating, producing strong acids and bases, causing fire and explosion hazard. Liquid attacks some plastics and rubber. Attacks many metals.
Waste DisposalWastewaters may be subjected to biological treatment. Concentrations may be further reduced by ozone treatment. High concentration wastes may be destroyed in special waste incinerators.
UN number
ADR/RID: 2076 IMDG: 2076 IATA: 2076
UN proper shipping name
Transport hazard class(es)
ADR/RID: 6.1 (8) IMDG: 6.1 (8) IATA: 6.1 (8)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.