Gamma Butyrolactone
Product identifier
- Product name: Gamma Butyrolactone
- CBnumber: CB9719491
- CAS: 96-48-0
- EINECS Number: 202-509-5
- Synonyms: GBL,Butyrolactone
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Gamma Butyrolactone
- Synonyms: GBL,Butyrolactone
- CAS: 96-48-0
- EC number: 202-509-5
- MF: C4H6O2
- MW: 86.09
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.
Development of hazardous combustion gases or vapours possible in the event of fire.
Advice for firefighters
In the event of fire, wear self-contained breathing apparatus.
Further information
Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 2 | Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent and neutralising material (e.g. Chemizorb? H ? , Merck Art. No. 101595). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Avoid generation of vapours/aerosols.
Hygiene measures
Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed.
hygroscopic
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
protective clothing
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type ABEK
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains.
Information on basic physicochemical properties
- Appearancecolorless liquid, clear
- Odourunpleasant
- Odour ThresholdNo data available
- pH4 - 5 at 100 g/l at 20 °C
- Melting point/freezing pointMelting point/range: -45 °C - lit.
- Initial boiling point and boiling range204 - 205 °C - lit.
- Flash point98 °C - closed cup
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limitsUpper explosion limit: 16 %(V) Lower explosion limit: 1,4 %(V)
- Vapour pressure ca.0,34 hPa at 20 °C - (calculated) 3 hPa at ca.52 °C - Tested according to Directive 92/69/EEC.
- Vapour density 2,97 - (Air = 1.0)
- Relative densityNo data available
- Water solubility1.000 g/l at 20 °C - OECD Test Guideline 105- miscible in all proportions
- Partition coefficient: n-octanol/waterlog Pow: -0,566 at 25 °C - OECD Test Guideline 107 - Bioaccumulation is not expected.
- Autoignition temperature435 °C at 1.013,25 hPa - DIN 51794
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: 2 mPa.s at 20 °C1,25 mPa.s at 25 °C1,25 mPa.s at 50 °C
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Relative vapor density
2,97 - (Air = 1.0)
Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Strong heating.
Incompatible materials
Strong acids, Strong bases, Strong oxidizing agents, Strong reducing agents, Zinc, Plastics
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityLC50 Inhalation - Rat - male and female - 4 h - > 5,1 mg/l (OECD Test Guideline 403)
LD50 Dermal - Guinea pig - > 5.000 mg/kg Remarks: (RTECS)
Result: No skin irritation - 20 h Remarks: (ECHA)
Result: Irreversible effects on the eye (OECD Test Guideline 405)
Application Route: Oral
Method: OECD Test Guideline 477 Result: negative
Toxicity
(OECD Test Guideline 203)
static test EC50 - Daphnia magna (Water flea) - > 500 mg/l - 48 h (Directive 67/548/EEC, Annex V, C.2.)
1.000 mg/l - 72 h (DIN 38412)
Persistence and degradability
Biodegradability aerobic - Exposure time 14 d
Result: 95 % - Readily biodegradable.
Biochemical Oxygen Demand (BOD)
(OECD Test Guideline 301C)
1.160 mg/g
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Additional ecological information
Biological effects:
Endangers drinking-water supplies if allowed to enter soil and/or waters in large quantities.
Discharge into the environment must be avoided.
Adsorbed organic bound halogens (AOX)
Remarks: Product does not contain any organic halogens.
Waste treatment methods
4-Butyrolactone is incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, alcohols, amines, strong and inorganic acids, strong bases.
Product
See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
Waste DisposalUse a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash.
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
Further information
Not classified as dangerous in the meaning of transport regulations.
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
Other Information
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.