2,4-Dichlorophenoxybutyric acid
Product identifier
- Product name: 2,4-Dichlorophenoxybutyric acid
- CBnumber: CB9776377
- CAS: 94-82-6
- EINECS Number: 202-366-9
- Synonyms: 2,4-DB,4-(2,4-dichlorophenoxy)butyric acid
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
Label elements
Pictogram(s)
- Signal wordWarning
H302 Harmful if swallowed
H411 Toxic to aquatic life with long lasting effects
P273 Avoid release to the environment.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: 2,4-Dichlorophenoxybutyric acid
- Synonyms: 2,4-DB,4-(2,4-dichlorophenoxy)butyric acid
- CAS: 94-82-6
- EC number: 202-366-9
- MF: C10H10Cl2O3
- MW: 249.09
Description of first aid measures
If inhaledMove the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delayed
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution. (ERG, 2016)
Indication of any immediate medical attention and special treatment needed
Bath and shampoo with soap and water to remove chemicals from skin and hair. Obtain medical treatment if irritation persists. Individuals with chronic skin disease or known sensitivity to these herbicides should either avoid using them or take strict precautions to avoid contact (respirator, gloves, etc.). Flush contaminating chemicals from eyes with copious amounts of clean water for 10-15 minutes. If irritation persists, obtain medical treatment. Chlorophenoxy cmpd
Extinguishing media
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: SMALL FIRE: Dry chemical, CO2, water spray or regular foam. LARGE FIRE: Water spray, fog or regular foam. Do not scatter spilled material with high-pressure water streams. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal. FIRE INVOLVING TANKS: Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)
Specific Hazards Arising from the Chemical
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state. (ERG, 2016)
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
Information on basic physicochemical properties
- Physical stateAmorphous Powder
- ColourOff-white
- Odour
Slightly phenolic
- Melting point/freezing point
118-120°C
- Boiling point or initial boiling point and boiling range
150 (0.2 torr)
- Flammability
no data available
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
no data available
- Auto-ignition temperature
no data available
- Decomposition temperature
no data available
- pH
no data available
- Kinematic viscosity
no data available
- Solubility
Water solubility: 46 ppm at 25 deg C.
- Partition coefficient n-octanol/water
log Kow= 3.53
- Vapour pressure
3.5X10-6 mm Hg at 25 deg (est)
- Density and/or relative density
1.369g/cm3
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
No rapid reaction with air. No rapid reaction with water.
Chemical stability
no data available
Possibility of hazardous reactions
2,4-DB is an organic acid. Neutralizes bases in exothermic reactions. Forms water soluble metal and amine salts. Hard water precipitates the calcium and magnesium salts from aqueous solutions of such salts.
Conditions to avoid
no data available
Incompatible materials
In an altered process to prepare 2,4-dichlorophenoxybutyric acid, the lactone /butyrolactone/ was added to the other components, and soon after, the reaction temperature reached 165 deg C, higher than the usual 160 deg C. Application of cooling failed to check the thermal runaway, and soon after reaching 180 deg C the vessel began to fail and an explosion and fire occurred.
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /hydrogen chloride/.
Acute toxicity
- Oral: LD50 Rat oral 700 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Not Likely to be Carcinogenic to Humans
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
4-(2,4-Dichlorophenoxy)butyric acid has been observed to undergo a beta-oxidation metabolism with soil microorganisms(1); the beta-oxidation yields (2,4-dichlorophenoxy)acetic acid (2,4-D) as the metabolite(1). At room temperatures, 4-(2,4-dichlorophenoxy)butyric acid was observed to degrade in a natural water die-away test (>12% in one week)(2); however, no degradation occurred in distilled water or in natural water that had been sterilized by addition of acid(2).
Bioaccumulative potential
Based upon a measured log Kow of 3.53(1) and a water solubility of 46 mg/l at 25 deg C(2), the BCF for 4-(2,4-dichlorophenoxy)butyric acid can be estimated to be about 280 and 70, respectively, from linear regression-derived equations(3,SRC). These BCF values suggest that bioconcentration in aquatic organisms is not important(SRC).
Mobility in soil
4-(2,4-Dichlorophenoxy)butyric acid has a pKa of 4.95 at 25 deg C(1); therefore, it will exist predominantly in the dissociated form at pHs of 5 or higher(SRC). The Koc of dissociated species can not be estimated accurately; however, the Koc of 4-(2,4-dichlorophenoxy)butyric acid has been experimentally measured to be 370 at pH 7.9(1). This Koc value suggests a classification of medium soil mobility(2,SRC).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.