成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

ChemicalBook >> journal list >> Synthesis-Stuttgart >>article
Synthesis-Stuttgart

Synthesis-Stuttgart

IF: 2.2
Download PDF

A New and Practical Synthesis of Vortioxetine Hydrobromide

Published:13 April 2015 DOI: 10.1055/S-0034-1380505
Yongjun Mao,?Luobin Jiang,?T. Chen,?H. He,?Gang Liu,?Han Wang

Abstract

Abstract A new and improved synthetic route to vortioxetine hydrobromide is established on a hectogram scale through three simple steps in 63% yield and with 99% purity (HPLC). The key step is the cyclization of the piperazine ring in the final step. Purification methods for the intermediates involved in the route are given.

Substances (2)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Piperazine 110-85-0 C4H10N2 628 suppliers $5.00-$1250.00
Vortioxetine hydrobromide 960203-27-4 C18H23BrN2S 385 suppliers $33.00-$2350.00

Similar articles

IF:5.3

Thermodynamic analysis and molecular dynamic simulation of the solubility of vortioxetine hydrobromide in three binary solvent mixtures

Journal of Molecular Liquids Yiming Ma , Yun Cao ,etc Published: 15 December 2018
IF:3.3

Weinreb Amide Approach to the Practical Synthesis of a Key Remdesivir Intermediate

The Journal of Organic Chemistry Yuanchao Xie, Tianwen Hu,etc Published: 18 March 2021
IF:1.8

Preventing aspartimide formation in Fmoc SPPS of Asp-Gly containing peptides — practical aspects of new trialkylcarbinol based protecting groups

Journal of Peptide Science Raymond Behrendt, Simon Huber,etc Published: 11 January 2016