Description

Estra-4,9,11-trien-17β-ol-3-one, also named as trenbolone, is a synthetic anabolic-androgenic steroid that belongs to the nandrolone group. Trenbolone is one of the most powerful anabolic steroids in existence. It is an injectable anabolic, used to gain large amounts of lean muscle and strength, whilst enhancing fat loss. The two most common forms of Trenbolone are Enanthate and Acetate. Trenbolone acetate is composed of short esters and enolates, so Acetate will work faster than Enanthate, and subsequently, cycles can be shorter[1]. Trenbolone acetate clears from the body faster than Enanthate because it has a shorter half-life.

Uses

Trenbolone is used as a growth promotant in animal husbandry[2]. Originally, it was used by veterinarians to fatten cattle before they were slaughtered. However, after observing anabolic effects in animals, bodybuilders began experimenting on themselves. The trials were resoundingly successful, but there were also serious side effects. Other classes of sterols are usually  wet, and Trenbolone is characterized by the fact that it is a dry compound. This means that Trenbolone does not convert to estrogen, so users of Trenbolone do not experience water retention or fat accumulation during a cycle. Trenbolone is also a multi-purpose compound that is used as a cutting or filler steroid. Because its anabolic effects clearly outweigh its fat-burning properties, Trenbolone is often used to gain weight.

Side effects

The most damaging side effect of Trenbolone is alterations in cholesterol, causing an increase in cardiovascular strain and left ventricular hypertrophy. Therefore, users with cardiovascular genetic predisposition should avoid Trenbolone[3]. It can lead to Possible Gynecomastia. Trenbolone significantly increases progesterone levels. Lactation occurs when the concentration of progesterone in a mans body is too high, leading to swollen nipples and potential gynecomastia. Trenbolone is highly androgenic and causes excessive sebum production, leading to oily skin and acne vulgaris. In particular, it can lead to an increase in visceral fat, and many anabolic steroids burn subcutaneous fat but increase visceral fat levels. It can also cause testosterone suppression and Male Pattern Baldness[4]. Psychologically, it can lead to irritability, anxiety, paranoia, and depression in the user.

References

[1] Richold M, et al. The genotoxicity of trenbolone, a synthetic steroid. Archives of Toxicology, 1988; 61: 249–258.

[2] Kumar V, et al. Acute pancreatitis secondary to the use of the anabolic steroid trenbolone acetate. Clinical Toxicology, 2019; 57.

[3] Borodi G, et al. Structural studies of trenbolone, trenbolone acetate, hexahydrobenzylcarbonate and enanthate esters. Journal of Molecular Structure , 2020; 1212: 128127.

[4] Smith L, et al. PSIV-9 Effects of polyamines and trenbolone acetate on proliferation rates of murine myoblasts. Journal of Animal Science, 2020; 98: 287–288.