中文名稱:喜樹(shù)堿

中文同義詞:喜樹(shù)堿;貝加靈;喜樹(shù)鹼;喜樹(shù)堿(天然);喜樹(shù)堿1G;拓?fù)涮婵迪嚓P(guān)物質(zhì)C;喜樹(shù)堿(標(biāo)準(zhǔn)品);喜樹(shù)堿((+)-喜樹(shù)堿)英文名稱:(+)-Camptothecin

英文同義詞:1,6-DIHYDROXY-7-GLUCURONOSYLFLAVONE;(20S)-CAMPTOTHECIN;CaMpetothecin;(4S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;CaMptothecin(NATURAL);CaMpathecin;4-ETHYL-4-HYDROXY-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLINE-3,14(4H,12H)DIONE;5,6-DIHYDROXY-7-GLUCURONOSYLFLAVONE

CAS號(hào):7689-03-4

分子式:C20H16N2O4

分子量:348.35

EINECS號(hào):444-280-6

喜樹(shù)堿性質(zhì)

熔點(diǎn)260°C(dec.)(lit.)

比旋光度D25+31.3°(inchloroform-methanol,8:2)

沸點(diǎn)482.73°C(roughestimate)

密度1.3112(roughestimate)

折射率1.5700(estimate)

儲(chǔ)存條件2-8°C

溶解度chloroform/methanol(4:1):4mg/mL

酸度系數(shù)(pKa)pKa10.83(Uncertain)

形態(tài)solid

顏色yellow

水溶解性insoluble

化學(xué)性質(zhì)：淡黃色針狀結(jié)晶。

用途：抗癌藥。用于胃癌、結(jié)腸癌、直腸癌、頭頸部圓柱瘤型癌和膀胱癌。