保存條件:-20*C 濃度:0.3 mg/ml 應用范圍:ELISA, WB 適應物種: 人動物植物 宿主:Rabbit 抗體英文名:Anti-BAX antibody 保質期:12個月 克隆性:多克隆 數(shù)量:大量 供應商:上海機純實業(yè)有限公司 規(guī)格:25 μ/100 uμ/200 μl Anti-BAX antibody Cat. No. JC120073 Package 25 μI/100 μl/200 μl Storage -20*C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Product overview Description Anti-BAX rabbit polyclonal antibody Applications ELISA, WB Immunogen Fusion protein of human BAX Reactivity Human, Mouse, Rat Content 0.3 mg/ml Host species Rabbit lg class Immunogen-specific rabbit lgG Purification Antigen afinity purification Anti-BAX antibody Target information Symbol BAX Full name BCL 2-associated X protein Synonyms BCL2L4 Swissprot Q07812
Target Background The protein encoded by this gene belongs to the BCL _2 protein family. BCL _2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL 2; and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of. the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome C. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode diferent isoforms, have been reported for this gene. Anti-BAX antibody Applications Western blotting Predicted band size:21 kDa Positive control:Human brain malignant glioma tissue, MCF7 Raji, Lovo and 293T cells Recommended dilution: 500-2000
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