Description
NFκB p65 Mouse Monoclonal Antibody(REK0132)
Cat. No.
REK0132
Immunogen
synthetic peptide coupled to KLH.
Concentration
1ug/ul
Specificity
The NFκB p65 mouse monoclonal antibody can detect endogenous NFκB p65 proteins.
MW
N/A
Substrate/Buffer
Phosphate buffered saline (PBS) with containing 0.02% sodium azide. pH 7.2.
Application
WB 1:5000
(Optimal dilutions should be determined by the end user)
Notes
NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Purity
Immunogen affinity purified
Clonality
Monoclonal
Isotype
IgG1
Alternative names
Nuclear Factor NF Kappa B p65 Subunit antibody, p65 NF kappaB antibody, Transcription Factor p65 antibody
天津銳爾康生物科技有限公司
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