?
?GAPDH Antibody
?
Cat#:PL0303047
?
Isotype:Rabbit Polyclonal IgG
?
Immunogen:Peptide derived from mouse GAPDH. ?
?
Purification:?Immunogen affinity purified
Storage Buffer:?PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, thereversible oxidative phosphorylation of glyceraldehyde-3-phosphatein the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease (2).
?
Alternate Names:
Glyceraldehyde-3-phosphate dehydrogenase; 38 kDa BFA-dependent ADP-ribosylation substrate; Aging-associated gene 9 protein; BARS-38; cb609; EC 1.2.1.12; G3PD; G3PDH; GAPD; Glyceraldehyde 3 phosphate dehydrogenase; Glyceraldehyde 3 phosphate dehydrogenase liver; Glyceraldehyde 3 phosphate dehydrogenase muscle; KNC-NDS6; MGC102544; MGC102546; MGC103190; MGC103191; MGC105239; MGC127711; MGC88685; OCAS, p38 component; OCT1 coactivator in S phase, 38-KD component; wu:fb33a10; G3P_HUMAN.?
?
Specificity Reaction:Mo, Rat
?
Application Notes:E: 1:500-1000?IHC: 1:100-500 IF: 1:100-500
?
Storage :
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted.
?
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
?
PLlabs公司可供應相應抗體的生物素、辣根過氧化物酶、熒光素(FITC、PE、 ?CY3、 CY5、 CY7、 PE- CY3/5/7)標記抗體,歡迎大家咨詢訂購。