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Anti-KIR3DS1 Polyclonal Antibody,Anti-KIR3DS1 Polyclonal Antibody
  • Anti-KIR3DS1 Polyclonal Antibody,Anti-KIR3DS1 Polyclonal Antibody

Anti-KIR3DS1 Polyclonal Antibody

價(jià)格 960.00 1600.00
包裝 50ul 100ul
最小起訂量 50ul
發(fā)貨地 北京
更新日期 2024-11-20
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產(chǎn)品詳情

中文名稱:Anti-KIR3DS1 Polyclonal Antibody英文名稱:Anti-KIR3DS1 Polyclonal Antibody
Gene ID: 3813Public Immunogen Range: Recombinant protein of human KIR3DS1
Subcellular Locations: Cell membrane Single-pass type I membrane proteinSwiss Prot: Q14943
保存: Store at -20°C. Avoid freeze / thaw cycles.別名: CD158E2;KIR-123FM;KIR-G1;NKAT-10;NKAT10
產(chǎn)品編號(hào): K006118P儲(chǔ)存液: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
純化方法: Affinity purification蛋白分子量: 43kDa
交叉反應(yīng): Human Mouse Rat克隆類型: Polyclonal Antibody
免疫原: Recombinant protein of human KIR3DS1品牌: solarbio
宿主: Rabbit稀釋比例: WB 1:500-2000. IHC 1:50-200.
性狀: 液體亞型: IgG
應(yīng)用: WB IHC英文名稱: Anti-KIR3DS1 Polyclonal Antibody
2024-11-20 Anti-KIR3DS1 Polyclonal Antibody Anti-KIR3DS1 Polyclonal Antibody 50ul/960.00RMB;100ul/1600.00RMB 960.00

背景資料

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
關(guān)鍵字: Anti-KIR3DS1 Polyclonal Antibody;抗體

公司簡(jiǎn)介

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