PPARβ/δ:17 nM (Kd)
PPARα:103 nM (Kd)
PPARγ:178 nM (Kd)
RARα:14 nM (IC50)
RARβ:14 nM (IC50)
RARγ:14 nM (IC50)
Human Endogenous Metabolite
DMSO:≥50mg / mL(166.42 mM)
H 2 O:<0.1 mg / mL(不溶)
* “≥”表示可溶,但飽和度未知。
4°C,避光
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[2]. Shaw N, et al. Retinoic acid is a high affinity selective ligand for the peroxisome proliferator-activated receptor beta/delta. J Biol Chem. 2003 Oct 24;278(43):41589-92.
[3]. Yu S, et al. Retinoic acid induces neurogenesis by activating both retinoic acid receptors (RARs) and peroxisomeproliferator-activated receptor β/δ (PPARβ/δ). J Biol Chem. 2012 Dec 7;287(50):42195-205.
[4]. Kam RK, et al. Retinoic acid synthesis and functions in early embryonic development. Cell Biosci. 2012 Mar 22;2(1):11.
[5]. Apfel C, et al. A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects. Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7129-33.
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