Product name
BEST1 Polyclonal Antibody
Isotype
IgG
Form
Lyophilized or Liquid
Tested applications
WB,IHC,ELISA
Species reactivity
Human,Mouse,Rat
Host Species
Rabbit
Purity
Affinity purification
?
Immunogen Information:
Immunogen
A synthetic peptide of human BEST1
Calculated molecular weight
57kDa/67kDa/69kDa
Observed molecular weight?
70kDa, 71kDa
Swiss Prot
O76090
Gene ID (NCBI)
7439
Alternative Names
ARB;BEST;BMD;RP50;TU15B;VMD2
Application Notes:
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
1:500 - 1:2000
IHC
1:50 - 1:200
?????????????????????????
Western blot analysis of extracts of various cell lines, using BEST1 antibody.
Immunohistochemistry of paraffin-embedded rat brain using BEST1 antibody.
???????????????????
Immunohistochemistry of paraffin-embedded human liver injury using BEST1 antibody.
Immunohistochemistry of paraffin-embedded human stomach using BEST1 antibody.
Background:
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.?
Storage:
Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
武漢華聯科生物技術有限公司
聯系商家時請?zhí)峒癱hemicalbook,有助于交易順利完成!