背景資料

AMPKα （PRKAA1） belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5’-prime-AMP-activated protein kinase （AMPK）. AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.

應用類型

The antibody can be used for ELISA （0.25 ug/ml）， Western blotting （2.5  5.0 ug/ml） and Immunohistochemistry （5 -25 ug/ml）.

免疫原

Synthetic peptide corresponding to the amino acid residues surrounding S487 of human PRKAA1

來源宿主

兔

反應性

經檢測驗證，可與人種屬來源的AMPKα蛋白發(fā)生免疫反應.

保存建議

提供的AMPKα抗體產品為100 ug 無色溶液，其濃度為0.25 mg/ml，溶解于包含有0.09% （W/V） 疊氮鈉的PBS緩沖液中.請將該AMPKα抗體產品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.