Mitotane (o,p'-DDD)
[Chemical Name]:
1,1-Dichloro-2,2-bis(2,4'-dichlorophenyl)ethane; 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
[Depression]:
A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
[Structure]:
[Formula]:C14H10Cl4
[Molecular Weight]:320.045
[CAS RN]:53-19-0
[Specification]:USP27/USP28
Appearance
White or off white
A
IR chromatograph conforms to characteristic peak of RS
B
UV chromatograph conforms to characteristic peak of RS
Melting range°C
75~81°C
Loss on drying
0.5%max
Residue on ignition
Organic volatile impurities
Meets the requirements
Assay (calculated on dried basis C14H10Cl4)
97.0~103.0%
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