product name: Picroside II
cas no.:39012-20-9
chemical name;(1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-Hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
molecular formula:C23H28O13
molecular weight: 512.47
solubility: soluble in Pyridine, Methanol
appearance: powder
purity by hplc: >98%
biological activity:Picroside II has potent anti-apoptotic activity against renal I/R injury, by suppressing the TLR4/NF-κB signaling pathway; Picroside II can protect the ischemic kidney against renal fibrosis and its mechanism may be through the inhibition of the long term inflammation.
關(guān)鍵字： 胡黃連苷II;Picroside II;Amphicoside II;6-Vanilloylcatalpol
上海水正生物醫(yī)藥科技有限公司（Arethusa-水正生物）是一家專業(yè)從事高純度天然藥物單體的研發(fā)及銷售的科技型企業(yè)。主營業(yè)務(wù)包括中藥對照品、植物標(biāo)準品、天然藥物活性單體、藥物雜質(zhì)分離純化、工藝開發(fā)研究及技術(shù)外包服務(wù)。
水正生物致力于構(gòu)建全球最有影響力的“大規(guī)模、高質(zhì)量天然產(chǎn)物庫”，為全球創(chuàng)新藥物研發(fā)機構(gòu)提供豐富的物質(zhì)基礎(chǔ)，為全產(chǎn)業(yè)發(fā)展搭建基礎(chǔ)性支撐平臺。該庫現(xiàn)已擁有3,000余種結(jié)構(gòu)類型多樣的天然化合物，幾乎涵蓋絕大部分已知的天然產(chǎn)物結(jié)構(gòu)類型，其中超過60%的產(chǎn)品無法從商業(yè)渠道獲得或現(xiàn)貨供應(yīng)商極少，它們源于650多種藥用植物或真菌（包括部分中藥），并且品種仍在持續(xù)豐富。