Human IFN-alpha / beta R1 Protein, His Tag (MALS verified)
分子別名(Synonym)
IFNAR1,IFNAR,CRF2-1,IFN-R-1,IFNAR-1
表達區(qū)間及表達系統(tǒng)(Source)
Human IFN-alpha / beta R1 Protein, His Tag (IF1-H5225) is expressed from human 293 cells (HEK293). It contains AA Lys 28 - Lys 436 (Accession # P17181-1).
Predicted N-terminus: Lys 28
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 49.0 kDa. The protein migrates as 65-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
干擾素α/β受體1(IFNAR1)也稱為細胞因子受體II類成員1、細胞因子受體家族2成員1(CRF2-1)、I型干擾素受體1、IFNAR,屬于II型細胞因子受體族。IFNAR1/IFNAR包含四個纖維連接蛋白III型結(jié)構(gòu)域。IFNAR1與IFNAR2結(jié)合形成I型干擾素受體。IFNAR1是干擾素α和β的受體。IFNAR1可以在沒有IFNAR2的幫助下轉(zhuǎn)導IFNB信號,并且不會激活Jak-STAT通路。
關(guān)鍵字: IFNAR1;IFNAR1蛋白;IFNAR1重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。