Human Cadherin-10 / CDH10 Protein, His Tag
分子別名(Synonym)
Cadherin-10,CDH10,T2-cadherin
表達區(qū)間及表達系統(tǒng)(Source)
Human Cadherin-10, His Tag (CA0-H52H5) is expressed from human 293 cells (HEK293). It contains AA Gly 55 - Ala 613 (Accession # Q9Y6N8-1).
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 64.2 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
鈣粘蛋白(Cadherins)是一大類細胞間粘附分子,參與多種細胞類型的細胞間粘附。在神經(jīng)系統(tǒng)中,鈣粘蛋白對發(fā)育的所有階段都至關(guān)重要,包括神經(jīng)管與外胚層的早期分離、神經(jīng)元和軸突的分離以及突觸的形成。這些分子介導使用細胞質(zhì)結(jié)構(gòu)域中兩個高度保守的氨基酸序列設(shè)計的鈣離子依賴性同型引物。其中一種鈣粘蛋白是Cadherin-10。Cadherin-10最初是從人腦中部分克隆的,但其mRNA也被證明存在于小鼠胸腺(稱為T2-cadherin)、小鼠睪丸以及小鼠、大鼠和雞的發(fā)育中的大腦和眼睛中。
關(guān)鍵字: Cadherin-10;CDH10蛋白;CDH10重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。