Galectin-9產(chǎn)品信息

英文名稱：Galactoside-binding lectin Galectin 9

中文名稱：半乳糖凝集素-9

靶點(diǎn)別稱：Galectin-9,LGALS9,Ecalectin

物種：Human

屬性：Protein

標(biāo)記：Biotin-labeled/Unconjugated

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>95% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in 20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲(chǔ)（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

Galectin-9用戶評(píng)價(jià)

Galectin-9分子背景

半乳凝素-9（LGALS9）也被稱為腫瘤抗原HOM-HD-21和凝集素。半乳凝素是一個(gè)蛋白質(zhì)家族，由其對(duì)β-半乳糖苷糖的結(jié)合特異性定義，如N-乙酰乳糖胺（Galβ1-3GlcNAc或Galβ1-2GlcNAc），可以通過N-連接或O-連接的糖基化與蛋白質(zhì)結(jié)合。半乳凝素-9對(duì)Forssman五糖具有很高的親和力，也是HAVCR2/TIM3的配體。此外，半乳凝素-9通過引起巨噬細(xì)胞活化和IL1B分泌來刺激受感染巨噬細(xì)胞的殺菌活性，從而限制細(xì)胞內(nèi)細(xì)菌的生長(zhǎng)。