中文名：血根堿水合物
英文名：Sanguinarine chloride hydrate
中文別名：氯化血根堿
英文別名：SANGUINARINE CHLORIDE|5578-73-4|Sanguinarium Chloride|Viadent|Sanguinarine chloride hydrate|Sanguinarine hydrochloride|Sanguinarine (chloride)|[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-, chloride (1:1)|CHEMBL490129|5578-73-4 (c
純度：≥97% (HPLC)
貨號：S101540
包裝：50mg、250mg
Cas號：5578-73-4
產(chǎn)品介紹：
Sanguinarine chloride is a benzophenanthridine alkaloid and potent, noncompetitive sodium/Potassium-ATPase Protein Inhibitors (Na+/K+ ATPase) inhibitor with anticancer properties. This product has been observed to induce apoptosis in cultured C6 rat glioblastoma cells potentially via a downregulative ability of extracellular singal-regulated and Akt signaling pathways. It is reported that sanguinarine also inhibits protein phosphatase 2C (PP2) and induces human promyelocytic leukemia cell line HL60 apoptosis throμgh the phosphorylation of p38, a PP2Cα substrate associated with caspase-3/7 activity. This compound posesses antimicrobial and anti-plaque qualities. Sanguinarine chloride is an inhibitor of MKP-1 and PP2. Isolated from the leaves and stems of Macleaya cordata and M. microcarpa.一個具有抗菌，消炎，抗氧化性能的天然產(chǎn)物。有抑制腫瘤細(xì)胞株擴(kuò)增和促凋亡作用。 A benzophenanthridine alkaloid and potent, noncompetitive Na+/K+-and Mg2++-ATPase inhibitor
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關(guān)鍵字： 氯化血根堿;SANGUINARINE CHLORIDE;5578-73-4;Sanguinarium Chloride
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