中文名：胰凝乳蛋白酶抑制劑
英文名：Chymostatin
中文別名：N-(Nα-羰基-Cpd-X-Phe-al)-Phe(Cpd = 環(huán)氧環(huán)氧環(huán)己烷)(環(huán)氧環(huán)氧環(huán)己烷= [S,S]-α-(2-亞氨基六氫-4-嘧啶基)甘氨酸)
英文別名：Chymostatin|51759-76-3|2-[[1-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-2-[[4-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]pentan-2-yl]amino]-2-oxoethyl]carbamoylamino]-3-phenylpropanoic acid|9076-44-2|n-{[1-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-
純度：≥95%
貨號：C113165
包裝：5mg、1mg
Cas號：9076-44-2
存儲溫度：-20°C儲存
產(chǎn)品介紹：
Chymostatin is a bioactive peptide protease inhibitor that contains chymostatin A as a major form. The compound specifically inhibits chymotrypsin (CTR) (ID50 = 150 ηg/ml), papain (ID50 = 7.5 μg/ml), and cathepsin G along with most cysteine proteases such as cathepsin A, B, H, and L. The compound has been noted as a strong inhibitor of cathepsins A, B, and C. Chymostatin at an effective concentration of 10 to 100 μM weakly inhibits human leukocyte Elastase-1. In rat muscle homogenates chymostatin inhibited the protease cathepsin B and other soluble Ca2+ activated proteases. In the same study, chymostatin decreased protein break down by 20-40% without inhibiting protein production.Chymostatin has been used in a study that determined that molecular calculations are useful for evaluating the interactions between ligands, including inhibitors and homologous enzymes, in docking models. Chymostatin has also been used in a study to investigate the norovirus protease as an attractive target for antiviral drμg development.
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關(guān)鍵字： N-(Nα-羰基-Cpd-X-Phe-al)-Phe(Cpd = 環(huán)氧環(huán)氧環(huán)己烷)(環(huán)氧環(huán)氧環(huán)己烷= [S,S]-α-(2-亞氨基六氫-4-嘧啶基)甘氨酸);Chymostatin;51759-76-3;2-[[1-(2-amino-1,4,5,6-tetrahydropyrimidin-6-yl)-2-[[4-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]pentan-2-yl]amino]-2-oxoethyl]carbamoylamino]-3-phenylpropanoic acid
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