中文名:JANEX-1,JAK3小分子抑制劑
英文名:JANEX-1
英文別名:JANEX-1|202475-60-3|WHI-P131|jak3 inhibitor i|Janex 1|4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol|4-(6,7-dimethoxyquinazolin-4-ylamino)phenol|4-((6,7-dimethoxyquinazolin-4-yl)amino)phenol|1J8Q49TR3I|CHEMBL405130|4-[(6,7-Dimethoxy-4-quinazolinyl)amino]ph
純度:98%
貨號:J126663
包裝:10mg、50mg、5mg
Cas號:202475-60-3
存儲溫度:-20°C儲存
產(chǎn)品介紹:
Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 μM). Janex-1 has no effect on JAK1, JAK2, or Zap/Syk or SRC tyrosine kinases. Janex-1 acts as a potent inhibitor of glioblastoma cell adhesion and migration and is also reported to block thrombin-induced platelet aggregation.A selective inhibitor of tyrosine kinase activity of JAK3
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