中文名：D-AP5,NMDA谷氨酸位點拮抗劑

英文名：(R)-(-)-2-Amino-5-phosphonopentanoic acid

中文別名：(R)-(-)-2-氨基-5-膦酰戊酸、D -2-氨基-5-膦酰戊酸、D(-)-2-氨基-5-膦戊酸

英文別名：D-AP5|79055-68-8|5-Phosphono-D-norvaline|(R)-2-Amino-5-phosphonopentanoic acid|d-APV|D-Norvaline, 5-phosphono-|(2R)-2-amino-5-phosphonopentanoic acid|D-(-)-2-Amino-5-phosphonopentanoic Acid|D-2-Amino-5-phosphonovaleric acid|D(-)-2-Amino-5-phosphonopentano

純度：98%

貨號：R137370

包裝：5mg、10mg、1mg

Cas號：79055-68-8

存儲溫度：-20°C儲存

產(chǎn)品介紹：

D-AP5 is a selective antagonist of the NMDA receptor. D(-)-2-Amino-5-phosphonovaleric acid is described to antagonize amino acid-induced synaptic excitations, blocking L-aspartate and dorsal root-evoked spinal neuron excitation, without affecting cholinergic excitation induced by exogenous acetylcholine administration. Evoked electrical activity of neurons is suppressed by D(-)-2-Amino-5-phosphonovaleric acid antagonism of motoneuronal depolarizations at the NMDAR. The (+)-stereoisomer of D(-)-2-Amino-5-phosphonovaleric acid demonstrates considerably diminished NMDAR activity as compared to this (-)-isomer.A selective antagonist of the NMDA receptor.

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