中文名:伊立替康
英文名:Irinotecan
中文別名:伊立替康
英文別名:MFCD00866307|AB00698464-10|CPT-11|D08086|(+)-7-ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate|[1,4'']Bipiperidinyl-1''-carboxylic acid 4,11-diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-9-y
純度:≥99%
貨號:I127961
包裝:100mg、500mg
Cas號:97682-44-5
存儲溫度:2-8°C儲存
產品介紹:
Irinotecan是一種Topoisomerase I抑制劑,作用于LoVo細胞和HT-29細胞,IC50分別為15.8 μM和5.17 μM。
Irinotecan hydrochloride has been used:
in combination with 5-fluorouracil for screening growth inhibitory functionality in MDA-MB-231 breast cancer cells.
in chemosensitivity screening of high-grade appendiceal (HGA) and low-grade appendiceal (LGA) organoids.
as a chemotherapeutic agent in the cytotoxicity studies in combination with heat shock proteins inhibitors (HPSC1) in HT29 colon cancer cells.
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關鍵字: 伊立替康;MFCD00866307;AB00698464-10;CPT-11
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