別名
4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl)benzamide
應(yīng)用
D4476 has been used as a casein kinase I inhibitor (CKI) in various experiments.
生化/生理作用
D4476 may prevent or enhance apoptosis. It triggers tumor suppressor p53 and impairs transcription factor E2F-1. D4476 is a potent, selective ATP-competitive inhibitor of CK1 (casein kinase 1).
特點和優(yōu)勢
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Sigma-Aldrich西格瑪奧德里奇(上海)貿(mào)易有限公司
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