Rabbit  Anti-CD27 Monoclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:CD27

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG

Entrez Gene:939

Swiss Prot:P26842

Source:KLH conjugated synthetic peptide derived from human CD27: 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-1000)
IHC-P(1:50-200)
IHC-F(1:50-200)
Flow-Cyt(1:50-100)
ICC(1:50-200)

Cross Reactive Species:Human
Mouse
Rat

僅供科研使用。不能用于人和動物治療等其它臨床診斷用！