Rabbit Anti-GDNF Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GDNF
IR:Immunogen Range:121-211/211
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2668
Swiss Prot:P39905
Source:KLH conjugated synthetic peptide derived from human GDNF:121-211/211
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Neurobiology. Neurotrophins. Neuroscience.
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:200-800)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： GDNF;glial cell line deri;Astrocyte derived tr; ATF 1;ATF1;ATF2;HFB1 ;GDNF;
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