Rabbit Anti-Collagen I Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Collagen I
IR:Immunogen Range:1321-1400/1464
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1277
Swiss Prot:P02452
Source:KLH conjugated synthetic peptide derived from human Collagen I C-terminal propeptide:1321-1400/1464
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
Sheep
Monkey
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Collagen I;Collagen type I;Alpha 1 type I colla;Alpha 2 type I colla;COL1A1;COL1A2;Collagen I alpha 1 p; Collagen I alpha 2 ;
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